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一例粪类圆线虫和耶氏肺孢子菌肺部混合感染的病例报告。

A case report of pulmonary coinfection of Strongyloides stercoralis and Pneumocystis jiroveci.

作者信息

Bava A J, Romero Mm, Prieto R, Troncoso A

机构信息

Laboratory of Parasitology, Infectious Diseases Hospital, Buenos Aires, Argentina.

出版信息

Asian Pac J Trop Biomed. 2011 Aug;1(4):334-6. doi: 10.1016/S2221-1691(11)60056-7.

Abstract

A case of pulmonary coinfection by Strongyloides stercoralis and Pneumocystis jiroveci has been detected in an AIDS patient treated in the Respiratory Intensive Care Unit of the Muñiz Hospital. At diagnosis, the patient presented cough with mucopurulent expectoration, dyspnea, fever, bilateral pulmonary infiltrates on the chest X-ray, negative bacilloscopy for acid fast bacteria and a CD4(+) T lymphocytes count of 52 cells/µL. The microbiological diagnosis was achieved by microscopic observation of the respiratory secretions obtained by bronchoalveolar lavage, while the wet mount examination revealed rhabditiform and filariform larvae of the nematode and foamy exudates, pathognomonic of the pulmonary pneumocystosis. It was the unique case of this association among about 3 000 samples performed in our laboratory in the last 10 years and diagnosed by microscopy. Other complementary stains (a rapid modification of Grocott, Kinyoun and Giemsa) were applied to the smears after the diagnosis of mycotic and parasitary infections achieved by fresh microscopy. Both physicians and microbiologists should take into account the possible coexistence of respiratory pathogens in immunocompromised patients, such as those with AIDS.

摘要

在穆尼兹医院呼吸重症监护病房接受治疗的一名艾滋病患者中,检测到一起由粪类圆线虫和耶氏肺孢子菌引起的肺部混合感染病例。诊断时,患者表现为咳嗽伴黏液脓性痰、呼吸困难、发热,胸部X线显示双侧肺部浸润,抗酸杆菌涂片检查阴性,CD4(+) T淋巴细胞计数为52个细胞/微升。微生物学诊断通过对支气管肺泡灌洗获得的呼吸道分泌物进行显微镜观察实现,湿片检查发现了线虫的杆状蚴和丝状蚴以及泡沫状渗出物,这是肺孢子菌病的特征性表现。这是过去10年在我们实验室进行的约3000份样本中,通过显微镜诊断出的这种关联的唯一病例。在通过新鲜显微镜检查确诊真菌和寄生虫感染后,对涂片应用了其他补充染色法(快速改良的格罗科特、金扬和吉姆萨染色法)。医生和微生物学家都应考虑免疫功能低下患者(如艾滋病患者)中呼吸道病原体可能共存的情况。

相似文献

本文引用的文献

1
Strongyloides stercoralis hyperinfection in a patient with AIDS.一名艾滋病患者发生的粪类圆线虫重度感染。
J Int Assoc Physicians AIDS Care (Chic). 2009 Jul-Aug;8(4):235-8. doi: 10.1177/1545109709336882. Epub 2009 Jun 4.
2
Pneumocystis carinii infection. Update and review.卡氏肺孢子虫感染。最新情况与综述。
Arch Pathol Lab Med. 2004 Sep;128(9):1023-7. doi: 10.5858/2004-128-1023-PCI.
3
Strongyloides stercoralis in the Immunocompromised Population.免疫功能低下人群中的粪类圆线虫
Clin Microbiol Rev. 2004 Jan;17(1):208-17. doi: 10.1128/CMR.17.1.208-217.2004.

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