Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France.
Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France; Addiction Department, CHU Lille, F-59000 Lille, France.
Schizophr Res. 2013 Jun;147(1):193-195. doi: 10.1016/j.schres.2013.03.011. Epub 2013 Apr 6.
There is very strong evidence that the prevalence of psychosis is elevated in migrant populations and that this risk persists into the second generation. However, these results have not been replicated in France, and the prevalence of psychotic disorders in the third generation of migrants remains unknown. Based on the Mental Health in General Population survey (n=37063), we report for the first time the increased prevalence of psychotic disorders in migrants in France, which persists into the second generation for a single psychotic episode (SPE) (OR=1.43, 95% CI [1.02-2.03], p<0.03) and into the third generation for recurrent psychotic disorder (RPD) (OR=1.78, 95% CI [1.45-2.18], p<0.0001) after adjustment for age, sex, level of education and cannabis use. Complementary statistical analyses of our sample showed a significantly higher risk of SPE in migrants from the French West Indies and Africa (χ(2)=17.70, p<0.01). These results are consistent with the socio-developmental model and the psychosis continuum hypothesis.
有非常有力的证据表明,精神病的患病率在移民群体中升高,而且这种风险持续到第二代。然而,这些结果在法国并未得到复制,移民的第三代中精神障碍的患病率仍然未知。基于一般人群心理健康调查(n=37063),我们首次报告了法国移民中精神障碍患病率增加,对于单次精神病发作(SPE)(OR=1.43,95%CI [1.02-2.03],p<0.03),这种情况持续到第二代,对于反复发作的精神病障碍(RPD)(OR=1.78,95%CI [1.45-2.18],p<0.0001),在调整年龄、性别、教育水平和大麻使用情况后仍然存在。对我们样本的补充统计分析显示,来自法属西印度群岛和非洲的移民 SPE 风险显著更高(χ(2)=17.70,p<0.01)。这些结果与社会发展模型和精神病连续体假说一致。