Tarricone Ilaria, Braca Mauro, Allegri Fabio, Barrasso Giuseppe, Bellomo Antonello, Berlincioni Vanna, Carpiniello Bernardo, Ceregato Alessio, Conforti Donati Marco, Defilippi Samuele, Del Vecchio Valeria, De Rosa Corrado, Ferrannini Luigi, Ferrari Silvia, Furio Maria Antonietta, Gramaglia Carla, La Cascia Caterina, Luciano Mario, Mulè Alice, Nardini Marcello, Podavini Francesca, Primavera Diego, Reggianini Corinna, Rigatelli Marco, Todarello Orlando, Turella Elena, Ventriglio Antonio, Zeppegno Patrizia, Fiorillo Andrea, Berardi Domenico
Department of Medical and Surgical Sciences, Bologna University, Bologna, Italy.
BMC Psychiatry. 2014 Jun 23;14:186. doi: 10.1186/1471-244X-14-186.
It has been frequently reported a higher incidence of psychotic disorders in immigrants than in native populations. There is, however, a lack of knowledge about risk factors which may explain this phenomenon. A better understanding of the causes of psychosis among first-generation migrants is highly needed, particularly in Italy, a country with a recent massive migration.
METHODS/DESIGN: The "Italian study on first-episode psychosis and migration (PEP-Ita)" is a prospective observational study over a two-year period (1 January 2012-31 December 2013) which will be carried out in 11 Italian mental health centres. All participating centres will collect data about all new cases of migrants with first-episode psychosis. The general purpose ("core") of the PEP-Ita study is to explore the socio-demographic and clinical characteristics, and the pathways to care of a population of first-episode psychosis migrants in Italy. Secondary aims of the study will be: 1) to understand risk and protective factors for the development of psychotic disorders in migrants; 2) to evaluate the correlations between psychopathology of psychotic disorders in migrants and socio-demographic characteristics, migration history, life experiences; 3) to evaluate the clinical and social outcomes of first-episode psychoses in migrants.
The results of the PEP-Ita study will allow a better understanding of risk factors for psychosis in first-generation migrants in Italy. Moreover, our results will contribute to the development of prevention programmes for psychosis and to the improvement of early intervention treatments for the migrant population in Italy.
经常有报道称，移民中精神障碍的发病率高于本地人口。然而，对于可能解释这一现象的风险因素却缺乏了解。非常需要更好地理解第一代移民中精神病的病因，尤其是在意大利，这个国家近期有大量移民涌入。
方法/设计：“意大利首发精神病与移民研究（PEP-Ita）”是一项为期两年（2012年1月1日至2013年12月31日）的前瞻性观察研究，将在11个意大利心理健康中心开展。所有参与中心将收集所有首发精神病移民新病例的数据。PEP-Ita研究的总体目标（“核心”）是探索意大利首发精神病移民群体的社会人口学和临床特征，以及其就医途径。该研究的次要目标将包括：1）了解移民中发生精神障碍的风险和保护因素；2）评估移民中精神障碍的精神病理学与社会人口学特征、移民史、生活经历之间的相关性；3）评估移民首发精神病的临床和社会结局。
PEP-Ita研究的结果将有助于更好地理解意大利第一代移民中精神病的风险因素。此外，我们的结果将有助于制定精神病预防方案，并改善意大利移民群体的早期干预治疗。
