Habib George, Artul Suheil, Hakim Geries
Rheumatology Clinic, Nazareth Hospital, 16000 Nazareth, Israel ; Department of Medicine, Carmel Medical Center, 34362 Haifa, Israel.
Case Rep Rheumatol. 2013;2013:829620. doi: 10.1155/2013/829620. Epub 2013 Mar 14.
Hiccups is a type of reflex that could happen secondary to different causes including drugs, especially systemic corticosteroids. Usually, high rather than regular doses of systemic steroids are incriminated, and this could explain the fact that very few cases of hiccups following regional corticosteroid treatment were reported. Here, we report the first case of hiccups in the English literature following intra-articular corticosteroid injection (IACI) at the knee joint and review all the previous reported cases of hiccups following regional corticosteroid treatment. Usually, this phenomenon of hiccups responds to regular antihiccups treatment; however, it is recommended not to repeat an IACI in a patient who had this adverse effect before due to an expected severe recurrent attack of hiccups afterwards.
呃逆是一种反射类型，可能继发于包括药物在内的不同病因，尤其是全身性皮质类固醇。通常，全身性类固醇高剂量而非常规剂量被认为与之有关，这可以解释为何区域皮质类固醇治疗后呃逆的病例报告极少。在此，我们报告英文文献中首例膝关节腔内皮质类固醇注射（IACI）后发生呃逆的病例，并回顾之前报道的所有区域皮质类固醇治疗后呃逆的病例。通常，这种呃逆现象对常规止呃治疗有反应；然而，由于预期随后会出现严重的呃逆复发，建议之前有过这种不良反应的患者不要再进行IACI。
