The Royal Marsden NHS Foundation Trust and the Institute of Cancer Research, Sutton, Surrey, UK.
BMC Med. 2013 Apr 10;11:104. doi: 10.1186/1741-7015-11-104.
The purpose of this article is to review the imaging techniques that have changed and are anticipated to change bladder cancer evaluation. The use of multidetector 64-slice computed tomography (CT) and magnetic resonance imaging (MRI) remain standard staging modalities. The development of functional imaging such as dynamic contrast-enhanced MRI, diffusion-weighted MRI and positron emission tomography (PET)-CT allows characterization of tumor physiology and potential genotypic activity, to help stratify and inform future patient management. They open up the possibility of tumor mapping and individualized treatment solutions, permitting early identification of response and allowing timely change in treatment. Further validation of these methods is required however, and at present they are used in conjunction with, rather than as an alternative to, conventional imaging techniques.
本文旨在回顾膀胱癌评估中已经改变和预计将会改变的影像学技术。多排 64 层计算机断层扫描(CT)和磁共振成像(MRI)的使用仍然是标准的分期方式。功能成像的发展,如动态对比增强 MRI、扩散加权 MRI 和正电子发射断层扫描(PET)-CT,允许对肿瘤生理学和潜在的基因型活性进行特征描述,以帮助分层和为未来的患者管理提供信息。它们为肿瘤定位和个体化治疗方案提供了可能,允许早期识别反应,并及时改变治疗方法。然而,这些方法还需要进一步验证,目前它们是与传统影像学技术结合使用,而不是替代传统影像学技术。