Suppr超能文献

临床医生对肥胖相关药物信息的接受程度:使用继续医学教育活动进行的定性评估。

Clinician uptake of obesity-related drug information: a qualitative assessment using continuing medical education activities.

机构信息

Johns Hopkins Bloomberg School of Public Health, Center for Human Nutrition, 198 Prince George St, Annapolis, MD 21401, USA.

出版信息

Nutr J. 2013 Apr 10;12:44. doi: 10.1186/1475-2891-12-44.

Abstract

BACKGROUND

Medications necessary for disease management can simultaneously contribute to weight gain, especially in children. Patients with preexisting obesity are more susceptible to medication-related weight gain. How equipped are primary care practitioners at identifying and potentially reducing medication-related weight gain? To inform this question germane to public health we sought to identify potential gaps in clinician knowledge related to metabolic adverse drug effects of weight gain.

METHODS

The study analyzed practitioner responses to the pre-activity questions of six continuing medical education (CME) activities from May 2009 through August 2010.

RESULTS

The 20,705 consecutive, self-selected respondents indicated varied levels of familiarity with adverse metabolic effects and psychiatric indications of atypical antipsychotics. Correct responses were lower than predicted for drug indications pertaining to autism (-17% predicted); drug effects on insulin resistance (-62% predicted); chronic disease risk in mental illness (-34% predicted); and drug safety research (-40% predicted). Pediatrician knowledge scores were similar to other primary care practitioners.

CONCLUSIONS

Clinicians' knowledge of medication-related weight gain may lead them to overestimate the benefits of a drug in relation to its metabolic risks. The knowledge base of pediatricians appears comparable to their counterparts in adult medicine, even though metabolic drug effects in children have only become prevalent recently.

摘要

背景

用于疾病管理的药物可能会同时导致体重增加,尤其是在儿童中。患有肥胖症的患者更容易受到与药物相关的体重增加的影响。初级保健医生在识别和潜在减少与药物相关的体重增加方面有多大能力?为了了解与公共卫生相关的这一问题,我们试图确定与药物引起的体重增加相关的代谢不良药物反应的临床医生知识方面的潜在差距。

方法

该研究分析了 2009 年 5 月至 2010 年 8 月期间 6 项继续医学教育(CME)活动的从业者对预活动问题的回答。

结果

20705 名连续的、自我选择的受访者表示对代谢不良药物副作用和非典型抗精神病药的精神指示的熟悉程度各不相同。对与自闭症相关的药物适应症(预测值的-17%)、药物对胰岛素抵抗的影响(预测值的-62%)、精神疾病中的慢性疾病风险(预测值的-34%)以及药物安全性研究(预测值的-40%)的正确回答低于预期。儿科医生的知识评分与其他初级保健医生相似。

结论

临床医生对与药物相关的体重增加的知识可能导致他们高估药物在代谢风险方面的益处。儿科医生的知识库与成人医学中的同行相当,尽管儿童的代谢药物作用最近才变得普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f60/3636058/e96416b8255b/1475-2891-12-44-1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验