Zhao Z D
Burn Institute, Southwest Hospital, Third Military Medical College, Chongqing.
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1990 Mar;6(1):50-2, 78-9.
Water contents of lung, heart, kidney, liver, gastro-intestines, and spleen in accident victims with good health (N = 10) and patients with postburn multiple organ failure (PBMOF) (N = 10) were measured. It was found that organ water content of all visceral organs was increased markedly in PBMOF patients. Moreover, the severity of increased organ water content was paralleled with the severity of organ failure. However, there were some differences between the results of the estimated blood volume in different organs. The pulmonary, cardiac and gastrointestinal residual blood water volumes were increased in these patients with PBMOF, indicating that congestion and/or sludging were superimposed in these organs. In contract, the renal and spleen residual blood water volumes were decreased, indicating that these organs were suffered from ischemia. On the other hand, the hepatic residual blood water volume was declined in these PBMOF without hepatic failure. However, it was increased in those with hepatic failure. These results suggested that the increase of organ water content might play an important role in the pathogenesis of organ failure.
对健康状况良好的事故受害者（N = 10）和烧伤后多器官功能衰竭（PBMOF）患者（N = 10）的肺、心脏、肾脏、肝脏、胃肠道和脾脏的含水量进行了测量。结果发现，PBMOF患者所有内脏器官的器官含水量均显著增加。此外，器官含水量增加的严重程度与器官衰竭的严重程度平行。然而，不同器官估计血容量的结果存在一些差异。这些PBMOF患者的肺、心脏和胃肠道残余血容量增加，表明这些器官存在充血和/或血液淤滞。相反，肾脏和脾脏的残余血容量减少，表明这些器官存在缺血。另一方面，在这些没有肝功能衰竭的PBMOF患者中，肝脏残余血容量下降。然而，在伴有肝功能衰竭的患者中，肝脏残余血容量增加。这些结果表明，器官含水量的增加可能在器官衰竭的发病机制中起重要作用。
