Zemtsov A, Taylor J S, Evey P, Dijkstra J
Department of Dermatology, Cleveland Clinic Foundation, Ohio 44195.
Cleve Clin J Med. 1990 May;57(3):301-3. doi: 10.3949/ccjm.57.3.301.
A case is reported of a 74-year-old white man who developed generalized allergic contact dermatitis from formaldehyde present in a liquid soap. The patient had a 2+ positive patch test reaction to formaldehyde, which was present as a preservative in the soap at 0.1% concentration. His dermatitis cleared when he switched to a nonformaldehyde-containing bar soap. The cause of the contact dermatitis was covert to both physician and patient before patch testing. Since registration with the Food and Drug Administration of formaldehyde-containing soaps is voluntary, it is likely that there are more soaps on the market than the six registered as of June 1988.
报告了一例74岁白人男性病例，其因液体肥皂中含有的甲醛而发生全身性过敏性接触性皮炎。患者对甲醛的斑贴试验反应呈2+阳性，甲醛作为防腐剂存在于肥皂中，浓度为0.1%。当他改用不含甲醛的条形肥皂后，皮炎症状消退。在进行斑贴试验之前，接触性皮炎的病因对医生和患者来说都是隐蔽的。由于向食品药品监督管理局注册含甲醛肥皂是自愿的，截至1988年6月，市场上可能存在比已注册的六种肥皂更多的含甲醛肥皂。
