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液体肥皂中甲醛引起的变应性接触性皮炎

Allergic contact dermatitis from formaldehyde in a liquid soap.

作者信息

Zemtsov A, Taylor J S, Evey P, Dijkstra J

机构信息

Department of Dermatology, Cleveland Clinic Foundation, Ohio 44195.

出版信息

Cleve Clin J Med. 1990 May;57(3):301-3. doi: 10.3949/ccjm.57.3.301.

Abstract

A case is reported of a 74-year-old white man who developed generalized allergic contact dermatitis from formaldehyde present in a liquid soap. The patient had a 2+ positive patch test reaction to formaldehyde, which was present as a preservative in the soap at 0.1% concentration. His dermatitis cleared when he switched to a nonformaldehyde-containing bar soap. The cause of the contact dermatitis was covert to both physician and patient before patch testing. Since registration with the Food and Drug Administration of formaldehyde-containing soaps is voluntary, it is likely that there are more soaps on the market than the six registered as of June 1988.

摘要

报告了一例74岁白人男性病例,其因液体肥皂中含有的甲醛而发生全身性过敏性接触性皮炎。患者对甲醛的斑贴试验反应呈2+阳性,甲醛作为防腐剂存在于肥皂中,浓度为0.1%。当他改用不含甲醛的条形肥皂后,皮炎症状消退。在进行斑贴试验之前,接触性皮炎的病因对医生和患者来说都是隐蔽的。由于向食品药品监督管理局注册含甲醛肥皂是自愿的,截至1988年6月,市场上可能存在比已注册的六种肥皂更多的含甲醛肥皂。

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