CARE Program, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Canada.
Complement Ther Med. 2013 Apr;21 Suppl 1:S48-53. doi: 10.1016/j.ctim.2011.08.006. Epub 2011 Sep 22.
To conduct a scoping review of paediatric CAM utilisation literature, in order to establish the depth and breadth of the field and identify gaps in knowledge regarding the epidemiology of CAM use.
A CAM and paediatric search strategy was developed and run in three databases (Medline, Embase, Amed) in June 2006. It was revised and rerun in February 2010. Utilisation studies about paediatric CAM were selected if they had an English or French abstract. Data were extracted into an excel table by one individual.
152 paediatric CAM utilisation studies were identified as of February 2010, 136 were fulltext English. There was variation in how CAM was defined: vitamins were included in 35 studies, excluded in 12 studies and not mentioned in 40; while prayer was included in 64, excluded in 9, and not mentioned in 39. Over half of the studies identified were from North America. The majority of studies were conducted in conventional health settings. The four most commonly studied subpopulations were cancer, asthma, autistic spectrum disorder, and attention deficit hyperactivity disorder. Eighteen percent of studies did not report on the period of assessment used. Twenty-seven percent of studies inquired about adverse events and 32% inquired about costs and insurance coverage.
There are substantial paediatric utilisation data available but some subpopulations remain poorly researched. The need for transparent utilisation data remains important in order to help prioritize safety and efficacy research.
对儿科 CAM 使用文献进行范围综述,以确定该领域的深度和广度,并确定有关 CAM 使用的流行病学知识方面的差距。
于 2006 年 6 月在三个数据库(Medline、Embase、Amed)中制定并运行 CAM 和儿科搜索策略。于 2010 年 2 月对其进行修订并重新运行。如果使用英文或法文摘要的儿科 CAM 利用研究符合条件,则选择该研究。由一个人将数据提取到一个 excel 表中。
截至 2010 年 2 月,共确定了 152 项儿科 CAM 使用研究,其中 136 项为全文英文。CAM 的定义存在差异:35 项研究将维生素包括在内,12 项研究将其排除在外,40 项研究未提及;而 64 项研究将祈祷包括在内,9 项研究将其排除在外,39 项研究未提及。确定的研究中有一半以上来自北美。大多数研究都是在常规医疗环境中进行的。研究最多的四个亚人群是癌症、哮喘、自闭症谱系障碍和注意缺陷多动障碍。18%的研究未报告使用的评估期。27%的研究询问了不良事件,32%的研究询问了成本和保险覆盖范围。
目前有大量儿科利用数据,但一些亚人群的研究仍不充分。为了帮助确定安全性和有效性研究的优先级,仍然需要透明的利用数据。