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针对个体患者的粘弹性咀嚼粘膜的有限元分析

Patient-specific finite element analysis of viscoelastic masticatory mucosa.

作者信息

Wakabayashi Noriyuki, Suzuki Tetsuya

机构信息

Department of Removable Partial Prosthodontics, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

J Dent Biomech. 2013 Apr 4;4:1758736013483298. doi: 10.1177/1758736013483298. Print 2013.

DOI:10.1177/1758736013483298
PMID:23580171
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3619231/
Abstract

The purpose of this study was to analyze the stress and strain inside of the oral mucosa in partially-edentulous patients. The patient-specific finite element models of the mucosa and the bone were constructed using the CT images and in-vivo surface measurement during a continuous load. The mean initial shear modulus of 8.3 × 10(-5) (GPa) and the mean relaxation time of 503 (s) were determined as the viscoelastic properties of the mucosa. The increase of the highest maximum compressive strain during the continuous loading was observed in all the patients, however; the intensity of strain was not in accordance with the thickness of the mucosa. It is suggested that the variations of the morphology and the initial modulus of the mucosa should be considered in the mathematical approaches to detect the mechanical responses of the oral mucosa.

摘要

本研究的目的是分析部分牙列缺损患者口腔黏膜内部的应力和应变。利用CT图像和连续加载过程中的体内表面测量数据,构建了黏膜和骨骼的患者特异性有限元模型。确定黏膜的粘弹性特性为平均初始剪切模量8.3×10^(-5)(GPa)和平均松弛时间503(s)。然而,在所有患者中均观察到连续加载过程中最高最大压缩应变的增加;应变强度与黏膜厚度不一致。建议在检测口腔黏膜力学响应的数学方法中应考虑黏膜形态和初始模量的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/ae6df5a53e99/10.1177_1758736013483298-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/3486a188f763/10.1177_1758736013483298-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/a85376b2195d/10.1177_1758736013483298-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/63c313ae7422/10.1177_1758736013483298-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/d5cc2a986982/10.1177_1758736013483298-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/ae6df5a53e99/10.1177_1758736013483298-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/3486a188f763/10.1177_1758736013483298-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/a85376b2195d/10.1177_1758736013483298-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/63c313ae7422/10.1177_1758736013483298-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/d5cc2a986982/10.1177_1758736013483298-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c23/3619231/ae6df5a53e99/10.1177_1758736013483298-fig5.jpg

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PLoS One. 2015 Jul 10;10(7):e0132552. doi: 10.1371/journal.pone.0132552. eCollection 2015.
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Biomechanical factors related to occlusal load transfer in removable complete dentures.与可摘全口义齿咬合负荷传递相关的生物力学因素。

本文引用的文献

1
Viscoelasticity of human oral mucosa: implications for masticatory biomechanics.口腔黏弹性:对咀嚼生物力学的影响。
J Dent Res. 2011 May;90(5):590-5. doi: 10.1177/0022034510396881. Epub 2011 Feb 14.
2
Strain analysis of maxillary complete denture with three-dimensional finite element method.采用三维有限元法对上颌全口义齿的应变分析。
J Prosthet Dent. 2010 May;103(5):309-18. doi: 10.1016/S0022-3913(10)60064-9.
3
ERK regulates strain-induced migration and proliferation from different subcellular locations.细胞外调节蛋白激酶(ERK)从不同亚细胞位置调节应变诱导的迁移和增殖。
Biomech Model Mechanobiol. 2015 Aug;14(4):679-91. doi: 10.1007/s10237-014-0642-0. Epub 2014 Dec 20.
J Cell Biochem. 2010 Mar 1;109(4):711-25. doi: 10.1002/jcb.22450.
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Numerical investigation of the mechanical loading of supporting soft tissue for partial dentures.
Int J Prosthodont. 2009 Mar-Apr;22(2):201-3.
5
Comparison between complete denture and implant-retained overdenture: effect of different mucosa thickness and resiliency on stress distribution.全口义齿与种植覆盖义齿的对比:不同黏膜厚度和弹性对义齿基托下黏膜应力分布的影响。
Gerodontology. 2009 Dec;26(4):273-81. doi: 10.1111/j.1741-2358.2008.00268.x. Epub 2008 Dec 1.
6
Development of a three-dimensional finite element model of a human mandible containing endosseous dental implants. I. Mathematical validation and experimental verification.含骨内牙种植体的人体下颌骨三维有限元模型的建立。I. 数学验证与实验验证。
J Biomed Mater Res A. 2007 Jan;80(1):234-46. doi: 10.1002/jbm.a.30894.
7
Responses of jawbone to pressure.颌骨对压力的反应。
Gerodontology. 2004 Jun;21(2):65-70. doi: 10.1111/j.1741-2358.2004.00005.x.
8
Kinesiographic study of complete denture movement related to mucosa displacement in edentulous patients.
Pesqui Odontol Bras. 2003 Oct-Dec;17(4):356-61. doi: 10.1590/s1517-74912003000400011. Epub 2004 Apr 19.
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J Oral Rehabil. 2003 Nov;30(11):1062-9. doi: 10.1046/j.1365-2842.2003.01183.x.