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Direct visualization of death of neurones projecting to specific targets in the developing rat brain.

作者信息

Harvey A R, Robertson D, Cole K S

机构信息

Department of Anatomy and Human Biology, University of Western Australia, Nedlands, Perth.

出版信息

Exp Brain Res. 1990;80(1):213-7. doi: 10.1007/BF00228865.

DOI:10.1007/BF00228865
PMID:2358030
Abstract

The fluorescent dye diamidino yellow was injected into parts of the developing visual and auditory systems in the rat. The dye was retrogradely transported by projecting neurones and was found to stain pyknotic profiles within the labelled cell populations. It is thus possible to visualize directly the death of neurones which project axons to specific and identified target regions within the nervous system.

摘要

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本文引用的文献

1
Naturally occurring neuron death in the ganglion cell layer of the neonatal rat: morphology and evidence for regional correspondence with neuron death in superior colliculus.
Brain Res. 1981 Sep;254(2):203-15. doi: 10.1016/0165-3806(81)90032-8.
2
A sensitive period for ganglion cell degeneration and the formation of aberrant retino-fugal connections following tectal lesions in rats.大鼠顶盖损伤后神经节细胞变性及异常视网膜-视路连接形成的敏感期。
Neuroscience. 1982 Mar;7(3):583-94. doi: 10.1016/0306-4522(82)90065-3.
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Cell death: the significance of apoptosis.细胞死亡:细胞凋亡的意义
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Naturally occurring neuron death and its regulation by developing neural pathways.自然发生的神经元死亡及其受发育中神经通路的调控。
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Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat.有色大鼠视网膜神经节细胞和视神经轴突群体的产后变化。
J Comp Neurol. 1983 Sep 20;219(3):356-68. doi: 10.1002/cne.902190309.
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The dual origins of the olivocochlear bundle in the albino rat.白化大鼠橄榄耳蜗束的双重起源
J Comp Neurol. 1983 Sep 10;219(2):203-14. doi: 10.1002/cne.902190206.
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Regressive events in neurogenesis.神经发生中的退行性事件。
Science. 1984 Sep 21;225(4668):1258-65. doi: 10.1126/science.6474175.
8
Diamidino yellow dihydrochloride (DY . 2HCl); a new fluorescent retrograde neuronal tracer, which migrates only very slowly out of the cell.二盐酸双脒基黄(DY.2HCl);一种新型荧光逆行神经元示踪剂,其从细胞中移出的速度非常缓慢。
Exp Brain Res. 1983;51(2):179-91. doi: 10.1007/BF00237193.
9
Different origins of cochlear efferents in some bat species, rats, and guinea pigs.某些蝙蝠物种、大鼠和豚鼠中耳蜗传出神经的不同起源。
J Comp Neurol. 1987 Oct 1;264(1):56-72. doi: 10.1002/cne.902640106.
10
Cell death in the developing retinal ganglion cell layer of the wallaby Setonix brachyurus.
J Comp Neurol. 1987 Oct 1;264(1):14-23. doi: 10.1002/cne.902640103.