Sahu Ritesh, Patil Tushar B, Kori Prakash, Shukla Rakesh
Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2013 Apr 10;2013:bcr2013009100. doi: 10.1136/bcr-2013-009100.
Lacunar syndrome is a neurodeficit secondary to a deep cerebral lesion, usually because of microatheroma of small arteries. Ataxic hemiparesis (AH) is a lacunar syndrome with unilateral pyramidal weakness and ipsilateral ataxia. Thalamic tuberculoma, as a cause of AH, has not been previously described in the literature. We describe an elderly man who presented with left hemiparesis and ipsilateral ataxia. Clinical examination revealed upper motor neuron left facial paresis and left-sided hemiparesis. The patient had incoordination in left upper and lower limbs. Mantoux test was positive and erythrocyte sedimentation rate was elevated. MRI of brain showed a conglomerated hypointense lesion in the right thalamus with a peripheral hyperintensity on T1-weighted imaging and a hyperintense lesion in T2-weighted imaging with significant perilesional oedema, suggesting a tuberculoma. The patient was treated with antitubercular therapy and was symptomatically better at the 9 months follow-up.
腔隙综合征是继发于深部脑病变的神经功能缺损,通常由小动脉的微动脉粥样硬化引起。共济失调性偏瘫(AH)是一种腔隙综合征,表现为单侧锥体肌无力和同侧共济失调。丘脑结核瘤作为AH的病因,此前文献中尚未有过描述。我们报告一名老年男性,表现为左侧偏瘫和同侧共济失调。临床检查发现左侧上运动神经元性面瘫和左侧偏瘫。患者左上肢和下肢存在共济失调。结核菌素试验阳性,红细胞沉降率升高。脑部MRI显示右侧丘脑有一个聚集性低信号病变,在T1加权成像上周边呈高信号,T2加权成像上为高信号病变,周围有明显水肿,提示为结核瘤。患者接受了抗结核治疗,在9个月的随访中症状有所改善。