Baud David, Rouiller Sylvie, Hohlfeld Patrick, Tolsa Jean-Francois, Vial Yvan
Department of Obstetrics and Gynaecology and.
J Matern Fetal Neonatal Med. 2013 Nov;26(16):1595-601. doi: 10.3109/14767058.2013.795533. Epub 2013 May 15.
To compare the adverse neonatal and maternal outcomes after medically indicated and elective labor induction. Both induction groups were also compared to women with spontaneous onset of labor.
Retrospective cohort study of 13 971 women with live, cephalic singleton pregnancies who delivered at term (from 1997 to 2007). Adverse maternal and neonatal outcomes were compared between women who underwent an induction of labor in the presence and absence of standard medical indications.
Among 5090 patients with induced labor, 2059 (40.5%) underwent elective labor inductions, defined as inductions without any medical or obstetrical indication. Risks of cesarean or instrumental delivery, postpartum hemorrhage >500 ml, prolonged maternal hospitalization >6 days, Apgar<7 at 5 min of life, arterial umbilical cord pH<7.1, admission in neonatal intensive care unit (NICU) and prolonged NICU hospitalization >7 days were similar between nulliparous who underwent elective and medical labor induction. Similar results were obtained for multiparous. All the above mentioned risks, but the Apgar<7 at 5 min of life, were significantly increased after induction in comparison to spontaneous labor.
Elective induction of labor carries similar obstetrical and neonatal risks as a medically indicated labor induction. Thus, elective induction of labor should be strongly discouraged.
比较医学指征性引产和选择性引产术后新生儿及产妇的不良结局。同时将两组引产产妇与自然发动分娩的产妇进行比较。
对1997年至2007年足月分娩的13971例单胎头位活产孕妇进行回顾性队列研究。比较有和没有标准医学指征情况下引产产妇的母婴不良结局。
在5090例引产患者中,2059例(40.5%)接受了选择性引产,即无任何医学或产科指征的引产。择期引产和医学指征性引产的初产妇剖宫产或器械助产、产后出血>500 ml、产妇住院时间延长>6天、出生后5分钟阿氏评分<7分、脐动脉血pH<7.1、入住新生儿重症监护病房(NICU)以及NICU住院时间延长>7天的风险相似。经产妇也得到了类似结果。与自然分娩相比,引产术后除出生后5分钟阿氏评分<7分之外,上述所有风险均显著增加。
选择性引产与医学指征性引产具有相似的产科和新生儿风险。因此,应强烈不鼓励选择性引产。