Melkie Abenezer, Addisu Dagne, Mekie Maru, Dagnew Enyew
Debre Tabor University, College of Health Sciences, Department of Midwifery, Ethiopia.
Heliyon. 2021 Mar 8;7(3):e06415. doi: 10.1016/j.heliyon.2021.e06415. eCollection 2021 Mar.
Failed induction increased maternal morbidity and mortality due to the associated complication which comes with cesarean section such as post partum hemorrhage and sepsis. The reports of previous articles on the proportion and associated factor of failed induction were variable and inconsistent. Therefore, this meta-analysis found out that the pooled proportion of failed induction and its associated factors in Ethiopia.
Systematic search was done by online databases (Pub Med, Web of Science, Google scholar and HINARI, and Ethiopian universities digital libraries). Unpublished studies that are found in the Ethiopian universities' digital libraries were used for this systematic review and meta-analysis study. Data were entered into Microsoft Excel and then exported to STATA 11 version statistical software for analysis. Heterogeneity assessed using the I statistic. The pooled proportion of failed induction and the odds ratio (OR) with a 95% confidence interval was showed using forest plots.
The overall proportion of failed induction was 23.58 % (95% CI: 13.72-33.44). Unfavorable Bishop Score [OR = 4.45, 95CI:2.44,8.12 ] intermediate Bishop Score [OR = 8.87, 95CI:4.62,17.05 ] and being primiparous woman [OR = 3.04, 95CI:1.74,5.53 ] were factors associated with failed induction of labour.
The prevalence of failed induction was high in Ethiopia. Unfavorable Bishop Score, intermediate Bishop Score, and primiparous were significantly associated with failed induction. Proper pelvis assessment for Bishop Score will be considered prior to initiating the induction of labor. Beside to this, the health professionals shall be aware of the relevance of cervical ripening for intermediate and unfavorable Bishop Score for pregnant women's before induction of labor.
引产失败会因剖宫产相关并发症(如产后出血和败血症)而增加孕产妇发病率和死亡率。以往关于引产失败比例及相关因素的文章报道各不相同且不一致。因此,本荟萃分析旨在找出埃塞俄比亚引产失败的合并比例及其相关因素。
通过在线数据库(PubMed、科学网、谷歌学术和HINARI以及埃塞俄比亚大学数字图书馆)进行系统检索。在埃塞俄比亚大学数字图书馆中找到的未发表研究被用于本系统评价和荟萃分析研究。数据录入Microsoft Excel,然后导出到STATA 11版本统计软件进行分析。使用I统计量评估异质性。使用森林图展示引产失败的合并比例和95%置信区间的比值比(OR)。
引产失败的总体比例为23.58%(95%CI:13.72 - 33.44)。Bishop评分不佳[OR = 4.45,95CI:2.44,8.12]、中等Bishop评分[OR = 8.87,95CI:4.62,17.05]以及初产妇[OR = 3.04,95CI:1.74,5.53]是与引产失败相关的因素。
埃塞俄比亚引产失败的患病率较高。Bishop评分不佳、中等Bishop评分和初产妇与引产失败显著相关。在开始引产之前应考虑对骨盆进行适当的Bishop评分评估。除此之外,卫生专业人员在引产之前应了解对于Bishop评分中等和不佳的孕妇进行宫颈成熟的相关性。