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选择性引产与自然分娩的关联及结局

Elective induction vs. spontaneous labor associations and outcomes.

作者信息

Glantz J Christopher

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

出版信息

J Reprod Med. 2005 Apr;50(4):235-40.

PMID:15916205
Abstract

OBJECTIVE

To determine factors and outcomes associated with elective medical induction of labor as compared with spontaneous labor in low-risk women.

STUDY DESIGN

Using a birth certificate database including 11,849 low-risk, laboring women, univariate and multiple logistic regression was used to evaluate demographic and obstetric factors associated with elective labor induction. Low risk was defined as singleton, vertex, 37-41 weeks' gestation, no prior cesarean section, and no presenting medical/obstetric diagnoses considered indications for cesarean or induction. Adverse neonatal outcome was defined as 1- or 5-minute Apgar score < 7, neonatal intensive care unit admission or respiratory distress. Spontaneously laboring women (n = 10,608) were compared with women who underwent induced labor for no apparent medical/obstetric reason (n = 1,241). Interventions and outcomes during and after labor induction were adjusted for relevant associated variables.

RESULTS

Odds ratios for epidural anesthesia, cesarean delivery and diagnoses of nonreassuring fetal heart rate patterns were independently increased following elective induction; odds ratios for cephalopelvic disproportion, instrumental delivery and adverse neonatal outcome were not. Maternal length of stay was 0.34 days longer with induction than with spontaneous labor (p < 0.0001). Slightly more induced labors ended before midnight.

CONCLUSION

As compared with spontaneous labor, elective labor induction is independently associated with more intrapartum interventions, more cesarean deliveries and longer maternal length of stay. Neonatal outcome is unaffected.

摘要

目的

确定低风险女性选择性引产与自然分娩相关的因素及结局。

研究设计

利用包含11849名低风险分娩女性的出生证明数据库,采用单因素和多因素逻辑回归来评估与选择性引产相关的人口统计学和产科因素。低风险定义为单胎、头先露、妊娠37 - 41周、无既往剖宫产史,且无当前医学/产科诊断被视为剖宫产或引产指征。不良新生儿结局定义为1分钟或5分钟阿氏评分<7、新生儿重症监护病房入院或呼吸窘迫。将自然分娩的女性(n = 10608)与无明显医学/产科原因而接受引产的女性(n = 1241)进行比较。对引产期间及之后的干预措施和结局进行相关变量调整。

结果

选择性引产后,硬膜外麻醉、剖宫产及胎儿心率异常诊断的比值比独立增加;头盆不称、器械助产及不良新生儿结局的比值比未增加。引产产妇的住院时间比自然分娩产妇长0.34天(p < 0.0001)。引产结束于午夜前的情况略多。

结论

与自然分娩相比,选择性引产与更多的产时干预、更多的剖宫产及更长的产妇住院时间独立相关。新生儿结局不受影响。

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