Thiri Kyaw Win, Nishikawa Noriko, Moritoyo Takashi, Tsujii Tomoaki, Iwaki Hirotaka, Nomoto Masahiro
Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, Japan.
Intern Med. 2013;52(8):871-6. doi: 10.2169/internalmedicine.52.9292. Epub 2013 Apr 15.
For patients with Parkinson's disease (PD), driving is challenging due to an impaired motor function and decreased attention capabilities. This study assessed the driving capacity in PD patients by comparing neurological signs.
The driving ability of PD patients was evaluated using a driving simulator (Safety Master NT-932) that tested the reaction time in response to traffic signals and steering wheel errors. We studied the correlations between the total Unified Parkinson's Disease Rating Scale (UPDRS) score, the UPDRS part III score, the subscores of the UPDRS part III score, age, PD disease duration, braking reaction time, steering wheel errors and total scores for driving safety test results. 'On' state regular PD licensed drivers (n=42; mean age: 63 years) in Hoehn and Yahr stages II-III participated after their cognitive status was confirmed using mini-mental state examinations.
The UPDRS scores, the UPDRS part III scores and the postural instability subscores exhibited significant (p<0.05) correlations with the number of steering wheel errors but not with the braking reaction time or the total safety scores of the test results.
The UPDRS is an established evaluation method used to estimate PD signs, although it is not sufficient alone for deciding whether PD patients should be allowed to drive. Our findings suggest that determining the driving ability using a driving simulator might be a useful adjunct to UPDRS scores in the assessment of PD patients who are active drivers. Estimating the driving ability requires complex measurements, including motor performance with perception of stimuli and attention.
对于帕金森病(PD)患者而言,由于运动功能受损和注意力下降,驾驶具有挑战性。本研究通过比较神经学体征评估PD患者的驾驶能力。
使用驾驶模拟器(Safety Master NT - 932)评估PD患者的驾驶能力,该模拟器测试对交通信号的反应时间和方向盘操作误差。我们研究了帕金森病统一评分量表(UPDRS)总分、UPDRS第三部分得分、UPDRS第三部分得分的子分数、年龄、PD病程、制动反应时间、方向盘操作误差与驾驶安全测试结果总分之间的相关性。使用简易精神状态检查确认认知状态后,Hoehn - Yahr分期为II - III期的“开”期常规PD持证驾驶员(n = 42;平均年龄:63岁)参与了研究。
UPDRS得分、UPDRS第三部分得分和姿势不稳子分数与方向盘操作误差数量呈显著(p < 0.05)相关,但与制动反应时间或测试结果的总安全得分无关。
UPDRS是一种用于评估PD体征的既定方法,尽管仅凭它不足以决定是否应允许PD患者驾驶。我们的研究结果表明,在评估活跃驾驶的PD患者时,使用驾驶模拟器确定驾驶能力可能是UPDRS得分的有用辅助手段。评估驾驶能力需要复杂的测量,包括对刺激的感知和注意力方面的运动表现。