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新型蒽醌类抗肿瘤抗生素DC92-B和DC92-D的结构

Structures of the novel anthraquinone antitumor antibiotics, DC92-B and DC92-D.

作者信息

Yasuzawa T, Saitoh Y, Sano H

机构信息

Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.

出版信息

J Antibiot (Tokyo). 1990 May;43(5):485-91. doi: 10.7164/antibiotics.43.485.

DOI:10.7164/antibiotics.43.485
PMID:2358401
Abstract

The structures of the new anthraquinone antitumor antibiotic DC92-B and its photodegradation product DC92-D were determined by their spectral studies. DC92-B and D are pluramycin antibiotics, related to hedamycin which possess a characteristic ring F and a side chain containing a cis-epoxide and terminal dimethyl.

摘要

通过光谱研究确定了新型蒽醌类抗肿瘤抗生素DC92 - B及其光降解产物DC92 - D的结构。DC92 - B和D属于多霉素类抗生素,与含有特征性F环以及包含顺式环氧化物和末端二甲基的侧链的赫地霉素相关。

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