Bork R, Vaupel P, Thews G
Anaesthesist. 1975 Feb;24(2):84-90.
In order to determine the interdependence of the parameters of the respiratory gas transport in rat blood (Sprague-Dawley) CO-2-equilibration curves in fully oxygenated and deoxygenated blood are measured. The results are presented in the form of pH-log P-CO-2-diagrams. O-2-dissociation curves of rat blood are registered at different CO-2 partial pressures. The P-02 at S-02 equals 50% ranged between 27.7 mm Hg for P-C0-2 equals 20 mm Hg. 35.1 mm Hg for P-C0-2 equals 40 mm Hg and 42.2 for P-C0-2 equals 60 mm Hg. Cartesian and alignment nomograms are constructed using CO-2 equilibration curves and O-2 dissociation curves. These nomograms give the interrelations between P-O-2, P-CO-2, pH and S-0-2 of rat blood. Separate nomograms are presented for Hb-concentrations of 10-13 g-% and 13.1-16 g-% because of great variations of Hb concentration in rat blood. If two of these values are known the nomograms permit the reading of the remaining paramters.
为了确定大鼠血液(斯普拉格 - 道利大鼠)呼吸气体运输参数之间的相互依存关系,测量了全氧合和脱氧血液中的二氧化碳平衡曲线。结果以pH - log P - CO₂图的形式呈现。在不同的二氧化碳分压下记录大鼠血液的氧解离曲线。当血氧饱和度(S - O₂)等于50%时,氧分压(P - O₂)在二氧化碳分压(P - CO₂)等于20 mmHg时为27.7 mmHg、P - CO₂等于40 mmHg时为35.1 mmHg以及P - CO₂等于60 mmHg时为42.2 mmHg之间变化。利用二氧化碳平衡曲线和氧解离曲线构建了直角坐标和对齐列线图。这些列线图给出了大鼠血液中P - O₂、P - CO₂、pH和S - O₂之间的相互关系。由于大鼠血液中血红蛋白(Hb)浓度变化很大,分别给出了Hb浓度为10 - 13 g-%和13.1 - 16 g-%时的列线图。如果已知其中两个值,列线图就可以读出其余参数。