Owens Corning Science and Technology Center, 2790 Columbus Road, Route 16, Granville, Ohio 43023-1200, USA.
Part Fibre Toxicol. 2013 Apr 12;10:13. doi: 10.1186/1743-8977-10-13.
The in-vitro dissolution rate of fibres is a good predictor of the in-vivo behavior and potential health effects of inhaled fibres. This study examines the effect of a new formaldehyde-free carbohydrate-polycarboxylic acid binder on the in-vitro dissolution rate of biosoluble glass fibres. Dissolution rate measurements in pH 7.4 physiological saline solution show that the presence of the binder on wool insulation glass fibres has no effect on their dissolution. There is no measurable difference between the dissolution rates of continuous draw fibres before and after binder was applied by dipping. Nor is there a measurable difference between the dissolution rates of a production glass wool sample with binder and that same sample after removal of the binder by low-temperature ashing. Morphological examination shows that swelling of the binder in the solution is at least partially responsible for the development of open channels around the glass-binder interface early in the dissolution. These channels allow fluid to reach the entire glass surface under the binder coating. There is no evidence of any delay in the dissolution rate as a result of the binder coating.
纤维的体外溶解速率是预测吸入纤维的体内行为和潜在健康影响的良好指标。本研究考察了一种新型无甲醛碳水化合物-多羧酸粘结剂对生物可溶性玻璃纤维体外溶解速率的影响。在 pH7.4 生理盐水溶液中的溶解速率测量表明，粘结剂的存在对羊毛绝缘玻璃纤维的溶解没有影响。在通过浸渍施加粘结剂前后，连续拉丝纤维的溶解速率没有可测量的差异。在低温灰化去除粘结剂后，生产玻璃棉样品的溶解速率与具有粘结剂的相同样品之间也没有可测量的差异。形态学检查表明，在溶解早期，粘结剂在溶液中的溶胀至少部分导致了玻璃-粘结剂界面周围的开放通道的形成。这些通道允许流体在粘结剂涂层下到达整个玻璃表面。没有证据表明粘结剂涂层会导致溶解速率延迟。
