Joyce B, Burns M V, Roy T M
University of Louisville School of Medicine, KY 40292.
J Ky Med Assoc. 1990 Jun;88(6):281-4.
Although relatively uncommon, Guillain-Barré syndrome remains the most frequent cause of sudden weakness in persons under the age of 40 years. While most patients enjoy spontaneous resolution of their neurologic deficits, death still occurs in some individuals who suffer secondary complications from profound respiratory muscle weakness. This review of patients with ascending paralysis who required intubation and mechanical ventilation underscores that the major factors which contribute to death and morbidity can be anticipated and largely avoided using a vigilant multidisciplinary approach.
尽管吉兰-巴雷综合征相对不常见，但它仍是40岁以下人群突发肌无力最常见的原因。虽然大多数患者的神经功能缺损可自发恢复，但仍有一些患者因严重呼吸肌无力引发的继发并发症而死亡。这篇对需要插管和机械通气的上行性麻痹患者的综述强调，通过警惕的多学科方法，可以预测并在很大程度上避免导致死亡和发病的主要因素。
