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斑秃的 Koebner 现象:拔毛后迅速出现。对发病机制和治疗的影响。

Koebner phenomenon in alopecia areata: rapid appearance after trichogram. Implications for the pathogenesis and therapy.

机构信息

National Coordinator of AIDA Group of Trichology, Bari, Italy.

出版信息

G Ital Dermatol Venereol. 2013 Apr;148(2):225-9.

PMID:23588149
Abstract

Anecdotical experiences indicate that Koebner phenomenon (KP) can also be observed in alopecia areata (AA). The present short report gives an account of what has been observed in some patients with remitting-relapsing AA in multiple patches, in whom the phenomenon was accidentally caused by perilesional Trichogram. The almost immediate appearance of relapses of the disease (1-7 days) and their evolution can be useful to understand the physiopathology of AA and and emphasize the compelling need for a rapid and appropriate diagnosis and treatment in the acute phase of AA, even with the active participation of the patient adequately trained. The method of trichogram should be reserved for cases in which non-invasive methods such as the Pull Test or Trichoscopy are not sufficient to verify the activity of the disease.

摘要

一些复发性多斑块型斑秃患者在皮损周围行毛发牵拉试验(Trichogram)后,偶然出现了斑秃同形反应(KP),本文报道了这一现象。斑秃同形反应的出现可提示疾病的复发,其出现时间为 1-7 天,有助于理解斑秃的病理生理学,强调了在斑秃的急性发作期,即使有经过适当培训的患者积极参与,也需要快速、恰当的诊断和治疗。当非侵入性方法(如拉发试验或毛发镜检查)不足以评估疾病活动度时,才考虑使用毛发牵拉试验。

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