儿童肌肉骨骼肿瘤的图像引导经皮芯针活检
Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children.
作者信息
Mitton Bryan, Seeger Leanne L, Eckardt Mark A, Motamedi Kambiz, Eilber Fritz C, Nelson Scott D, Eckardt Jeffrey J, Federman Noah
机构信息
*Department of Pediatrics, Division of Pediatric Hematology/Oncology ‡Department of Medicine, Division of Hematology/Oncology §Department of Surgery, Division of Surgical Oncology Departments of †Radiology ∥Pathology ¶Orthopedic Surgery, University of California, Los Angeles, Los Angeles CA.
出版信息
J Pediatr Hematol Oncol. 2014 Jul;36(5):337-41. doi: 10.1097/MPH.0b013e3182880de0.
The use of image-guided percutaneous core needle biopsy (PCNB) to obtain tissue diagnosis of musculoskeletal lesions has become the standard of care in adult patients with a success rate of over 80%. Previous reports indicate a similar success rate in diagnosing pediatric solid tumors. In this large study, we analyzed >10 years of data in which PCNB was used for tissue diagnosis of musculoskeletal lesions in children; we evaluated the histopathologic accuracy, anesthetic requirements, and complications of these procedures. In 122 children, tissue diagnosis was successfully obtained in 82% of cases, and there were 0 complications associated with the procedure. There was a significantly higher PCNB diagnostic success rate in malignant lesions (93%). These data suggest that the use of PCNB is a safe and effective means of diagnosing musculoskeletal lesions in children.
使用影像引导下经皮穿刺活检针活检（PCNB）获取肌肉骨骼病变的组织诊断已成为成年患者的标准治疗方法，成功率超过80%。既往报告显示，诊断儿童实体瘤的成功率与之相似。在这项大型研究中，我们分析了超过10年的数据，其中PCNB用于儿童肌肉骨骼病变的组织诊断；我们评估了这些操作的组织病理学准确性、麻醉需求和并发症。在122名儿童中，82%的病例成功获得组织诊断，且该操作无相关并发症。恶性病变的PCNB诊断成功率显著更高（93%）。这些数据表明，使用PCNB是诊断儿童肌肉骨骼病变的一种安全有效的方法。
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