Weigl Helene, Hohenberger Peter, Marx Alexander, Vassos Nikolaos, Jakob Jens, Galata Christian
Department of Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Division of Surgical Oncology & Thoracic Surgery, Department of Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Cancers (Basel). 2021 Nov 12;13(22):5659. doi: 10.3390/cancers13225659.
The aim of this study was to investigate diagnostic accuracy, safety and histologic results of ultrasound guided core needle biopsy (CNB) in patients with soft tissue lesions (STL) at a tertiary referral center.
A retrospective analysis of all consecutive patients undergoing ultrasound guided CNB for STL at our sarcoma outpatient service between January 2015 and August 2020 was performed.
A total of 392 patients were identified. Main histologic entities were sarcomas, lipomas and desmoid tumors. Biopsy was performed in an outpatient setting in 87.6% of the cases. Conclusive biopsies were obtained in 88.5% of the cases. In patients who underwent surgical resection after CNB, the concordance of dignity, tumor entity and histopathological grading between biopsy and resection specimen were 97.2%, 92.7% and 92.5% respectively. The risk of inconclusive CNB was highest in intraabdominal or retroperitoneal tumors (19.5%) and lowest in lesions at the lower extremity (4.4%). Major complications after CNB occurred in three cases (0.8%). No case of biopsy tract seeding was observed during the study period.
Ultrasound guided CNB for STL at first presentation in a dedicated surgical outpatient setting is a safe procedure and yields a high diagnostic accuracy.
本研究旨在调查在一家三级转诊中心，超声引导下粗针活检（CNB）对软组织病变（STL）患者的诊断准确性、安全性及组织学结果。
对2015年1月至2020年8月期间在我们肉瘤门诊接受超声引导下STL的CNB的所有连续患者进行回顾性分析。
共确定了392例患者。主要组织学类型为肉瘤、脂肪瘤和硬纤维瘤。87.6%的病例在门诊进行活检。88.5%的病例获得了确定性活检结果。在CNB后接受手术切除的患者中，活检与切除标本之间在肿瘤性质、肿瘤类型和组织病理学分级方面的一致性分别为97.2%、92.7%和92.5%。CNB结果不确定的风险在腹内或腹膜后肿瘤中最高（19.5%），在下肢病变中最低（4.4%）。CNB后发生了3例主要并发症（0.8%）。在研究期间未观察到活检道种植的病例。
在专门的外科门诊对初诊的STL进行超声引导下CNB是一种安全的操作，诊断准确性高。
