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尿道狭窄上方的鳞状细胞癌:病例报告及文献复习

Squamous cell carcinoma on top of urethral stricture: case report and review of the literature.

作者信息

Kotb Ahmed Fouad, Attia Doaa, Ismail Asmaa Mohamed, Elabbady Ahmed

机构信息

Urology department, Faculty of Medicine, Alexandria University, Al Khartom Square, Azarita, Alexandria, Egypt.

出版信息

Ecancermedicalscience. 2013 Apr 11;7:304. doi: 10.3332/ecancer.2013.304. Print 2013.

Abstract

INTRODUCTION

Urethral stricture is a common urological condition, resulting from trauma or venereal infections. The aim of our study was to report a rare case of squamous cell carcinoma of the penis and pseudoepitheliomatous hyperplasia (PEH) of scrotal skin, on top of repeatedly managed urethral stricture which was of unknown aetiology.

METHODS

A Medline search of publications studying the association of urethral stricture with penile cancer was done.

RESULTS

Two case reports were identified that described two occurrences, which were separated by a few months.

CONCLUSION

Repeated management of urethral stricture with visual urethrotomy or urethral dilation may result in a chronic inflammatory status, predisposing to PEH and squamous cell carcinoma of the genital organs.

摘要

引言

尿道狭窄是一种常见的泌尿系统疾病,由创伤或性传播感染引起。我们研究的目的是报告一例罕见的阴茎鳞状细胞癌和阴囊皮肤假上皮瘤样增生(PEH)病例,该病例发生在病因不明且经多次治疗的尿道狭窄基础上。

方法

对研究尿道狭窄与阴茎癌关联的出版物进行了医学文献数据库检索。

结果

确定了两篇病例报告,描述了两起相隔数月的事件。

结论

反复进行直视下尿道切开术或尿道扩张术治疗尿道狭窄可能导致慢性炎症状态,易引发生殖器器官的PEH和鳞状细胞癌。

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