麻疹病毒对人肠道黏膜的细胞病变效应。

Cytopathic effects of measles virus on the human intestinal mucosa.

作者信息

Jirapinyo P, Thakerngpol K, Chaichanwatanakul K

机构信息

Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Pediatr Gastroenterol Nutr. 1990 May;10(4):550-4. doi: 10.1097/00005176-199005000-00022.

DOI:10.1097/00005176-199005000-00022

PMID:2358987

Abstract

We reported a case of measles with diarrhea in an infant. Capsule biopsy samples of intestinal mucosa taken 14 days after onset of fever was damaged and had low disaccharidase activities. Virus particles were found in the damaged villous cell. Second intestinal mucosa biopsy samples taken 28 days after onset of fever was found to be normal in structure, but lactase and sucrase activities were still low. Mucosal damage by virus particles was the cause of diarrhea in our infant.

摘要

我们报告了一例婴儿麻疹伴腹泻的病例。发热开始14天后采集的肠黏膜胶囊活检样本受损，二糖酶活性较低。在受损的绒毛细胞中发现了病毒颗粒。发热开始28天后采集的第二次肠黏膜活检样本结构正常，但乳糖酶和蔗糖酶活性仍然较低。病毒颗粒造成的黏膜损伤是我们这名婴儿腹泻的原因。