Suppr超能文献

经会阴特伦德伦伯氏位行腹会阴联合切除术的12年经验

A 12-year experience of the Trendelenburg perineal approach for abdominoperineal resection.

作者信息

Toshniwal Sumeet, Perera Marlon, Lloyd David, Nguyen Hung

机构信息

Launceston General Hospital, Launceston, Tasmania, Australia.

出版信息

ANZ J Surg. 2013 Nov;83(11):853-8. doi: 10.1111/ans.12137. Epub 2013 Apr 17.

Abstract

BACKGROUND

The abdominoperineal resection (APR) is the current accepted surgical technique for low rectal cancers. Negative circumferential surgical margins are an important prognostic indicator and are best obtained by producing a cylindrical specimen. The 'ideal' approach to produce such specimen is debated between a standard lithotomy position and turning the patient in the prone position in the later stages of the procedure. We aimed to assess results of perineal morbidity and oncological outcomes following the lithotomy approach at a single institution.

METHODS

Data were collected retrospectively at a single institution. All patients undergoing the APR for low rectal cancers were included in the current study. Patients underwent this procedure in the standard lithotomy position and a mucocutaneous flap was not routinely used for closure of the perineal wound. The primary outcome measures in this study were local and systemic tumour recurrence and overall patient survival.

RESULTS

Fifty-three patients undergoing APR were included in the current study. Majority of patients (87%) received neoadjuvant therapy. Perineal morbidity was observed in 11% of patients loco-regional recurrence occurred in 4% at 5 years. One-, 3- and 5-year survival was 87, 75 and 66%, respectively. Patients with T3/4 disease and positive circumferential surgical margins had significantly poorer survival outcomes.

CONCLUSION

APR can be performed in the lithotomy position with acceptable perineal morbidity and oncological safety. Negative circumferential margins can be achieved reliably by producing a cylindrical specimen with this position.

摘要

背景

腹会阴联合切除术(APR)是目前公认的低位直肠癌手术技术。阴性切缘是一个重要的预后指标,通过制作圆柱形标本可最佳地获得。在标准截石位和手术后期将患者转为俯卧位之间,对于制作这种标本的“理想”方法存在争议。我们旨在评估在单一机构采用截石位方法后的会阴并发症结果和肿瘤学结局。

方法

在单一机构进行回顾性数据收集。所有接受低位直肠癌APR手术的患者纳入本研究。患者采用标准截石位进行该手术,会阴伤口闭合不常规使用黏膜皮瓣。本研究的主要结局指标是局部和全身肿瘤复发以及患者总体生存情况。

结果

本研究纳入了53例行APR手术的患者。大多数患者(87%)接受了新辅助治疗。11%的患者出现会阴并发症,5年时局部区域复发率为4%。1年、3年和5年生存率分别为87%、75%和66%。患有T3/4期疾病且切缘阳性的患者生存结局明显较差。

结论

APR手术可在截石位进行,会阴并发症和肿瘤学安全性可接受。通过在此体位制作圆柱形标本可可靠地实现阴性切缘。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验