Naranji Ishvar, Zakri Rhana H, Liston Thomas
Department of Urology, Worthing Hospital, West Sussex BN11 2DH, UK.
J Med Case Rep. 2013 Apr 16;7:105. doi: 10.1186/1752-1947-7-105.
Mantle cell lymphoma is one of the several subtypes of non-Hodgkin's lymphoma. Mantle cell lymphoma is the rarest of the subtypes, accounting for about 6% of all non-Hodgkin's lymphoma cases in the United States and Europe. Lymphoid neoplasms of the urinary tract and male genital organs are relatively rare, accounting for less than 5% of extranodal lymphomas. We present a rare case of mantle cell lymphoma infiltrating the ureter causing pelvi-ureteric junction obstruction on tissue diagnosis.
A 78-year-old Caucasian woman was referred to our department with right flank pain, pyrexia and features of a urinary tract infection. A nephrostogram revealed a grossly distended right pelvicalyceal system in a pelvi-ureteric junction obstruction pattern. She underwent an elective pyeloplasty after her acute management and the results of histological examination revealed mantle cell lymphoma.
We describe a rare presentation of mantle cell lymphoma as a pelvi-ureteric junction obstruction. To the best of our knowledge, there has not been any previously published report of the above finding. Our patient had a history of a previous lymphoma but the aim of this manuscript is to highlight a possible presentation rather than determining whether the mantle cell lymphoma was de novo or a transformation from her previous splenic lymphoma with villous lymphocytes.
套细胞淋巴瘤是非霍奇金淋巴瘤的几种亚型之一。套细胞淋巴瘤是最罕见的亚型，在美国和欧洲约占所有非霍奇金淋巴瘤病例的6%。泌尿系统和男性生殖器官的淋巴样肿瘤相对罕见，占结外淋巴瘤的比例不到5%。我们报告一例罕见的套细胞淋巴瘤病例，经组织学诊断发现其浸润输尿管导致肾盂输尿管连接处梗阻。
一名78岁的白种女性因右侧腰痛、发热及尿路感染症状转诊至我科。肾造影片显示右侧肾盂肾盏系统严重扩张，呈肾盂输尿管连接处梗阻模式。在急性处理后，她接受了择期肾盂成形术，组织学检查结果显示为套细胞淋巴瘤。
我们描述了套细胞淋巴瘤表现为肾盂输尿管连接处梗阻这一罕见情况。据我们所知，此前尚无关于上述发现的报道。我们的患者既往有淋巴瘤病史，但本文的目的是强调一种可能的表现形式，而非确定套细胞淋巴瘤是新发的还是由她之前的脾绒毛淋巴细胞性淋巴瘤转化而来。
