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73例椎管内神经鞘瘤的临床分析

Clinical analysis of 73 cases of intraspinal nerve sheath tumor.

作者信息

Liu Jian-Xiang, Zhou Hai-Zhen, Yang Shu-Hua, Shao Zeng-Wu, Zheng Qi-Xin, Yang Cao, Gao Yong, Raj Shrestha, Mohan Dhakal Rabi

机构信息

Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):258-261. doi: 10.1007/s11596-013-1107-x. Epub 2013 Apr 17.

Abstract

Seventy-three patients with spinal nerve sheath tumor who were surgically treated in our hospital during the years 2004-2010 were retrospectively reviewed with respect to recovery of neurological function, recurrence of the tumor and occurrence of kyphotic deformities. Preoperative clinical manifestations, imaging data, surgical records and follow-up results were comprehensively analyzed. The follow-up duration was 12-60 months with an average of 32.0 months. Out of the 73 cases enrolled, 69 had gradual recovery of sensation, motor and sphincter functions 1 week to 3 months after operation. Forty-six cases had incomplete paralysis, whose American Spinal Injury Association (ASIA) grades, however, were gradually increased during the follow-up period, 4 cases had no significant improvement of the clinical symptoms and no change in ASIA grades during the follow-up period. Two cases had postoperative recurrence of the tumor. There were no deaths, no spinal instability, and no kyphotic malformations found in any cases. Our study indicated that complete removal of the tumor is important for good recovery, and an ideal surgical method may reduce the recurrence of the tumor or the occurrence of complications.

摘要

回顾性分析2004年至2010年期间在我院接受手术治疗的73例脊神经鞘瘤患者的神经功能恢复、肿瘤复发及脊柱后凸畸形发生情况。综合分析术前临床表现、影像学资料、手术记录及随访结果。随访时间为12至60个月,平均32.0个月。73例患者中,69例术后1周~3个月感觉、运动及括约肌功能逐渐恢复。46例不完全瘫痪患者,随访期间美国脊髓损伤协会(ASIA)分级逐渐提高,4例随访期间临床症状无明显改善,ASIA分级无变化。2例术后肿瘤复发。所有病例均无死亡、无脊柱不稳及脊柱后凸畸形。我们的研究表明,完整切除肿瘤对良好恢复很重要,理想的手术方法可能会减少肿瘤复发或并发症的发生。

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