Tan Lee A, Moftakhar Roham, Lopes Demetrius K
Department of Neurosurgery, Rush University Medical Center, Chicago, IL, USA.
J Cerebrovasc Endovasc Neurosurg. 2013 Mar;15(1):30-3. doi: 10.7461/jcen.2013.15.1.30. Epub 2013 Mar 31.
Treatment options of ruptured vertebrobasilar fusiform aneurysms (VFA) are limited and often carry significant mortality and morbidity. We report the use of Pipeline Embolization Device (PED) to successfully treat a patient with a ruptured vertebrobasilar fusiform aneurysm (VFA) who presented with subarachnoid hemorrhage (SAH). A 73 year-old man with a history of cardiac stent placement seven days earlier presented with Hunt-Hess II SAH. He was taking aspirin and clopidogrel. Computed tomography angiogram revealed a large vertebrobasilar fusiform aneurysm. Microsurgical treatment options are technically challenging and carry high risk. He underwent endovascular treatment of the ruptured VFA using overlapping PEDs. Five PEDs were placed in a telescoping fashion to reconstruct the affected portions of the left vertebral and basilar arteries. An additional 2-mm blister aneurysm in the right vertebral artery was also discovered during the conventional cerebral angiography and was treated with one additional PED. The patient remained neurologically intact after the procedure. He was continued on aspirin and clopidogrel. Follow-up magnetic resonance imaging at three months demonstrated patency of the stents without any evidence of ischemic change. Follow-up conventional cerebral angiogram at six months demonstrated thrombosis of the VFA and reconstruction of the vertebrobasilar system. The patient remained clinically well. An endovascular approach using PEDs can be a safe and effective treatment option for ruptured VFA in selected cases.
破裂性椎基底动脉梭形动脉瘤(VFA)的治疗选择有限,且往往伴有显著的死亡率和发病率。我们报告了使用Pipeline栓塞装置(PED)成功治疗一名患有破裂性椎基底动脉梭形动脉瘤(VFA)并伴有蛛网膜下腔出血(SAH)的患者。一名73岁男性,7天前有心脏支架置入史,现出现Hunt-Hess II级SAH。他正在服用阿司匹林和氯吡格雷。计算机断层血管造影显示一个大型椎基底动脉梭形动脉瘤。显微外科治疗选择在技术上具有挑战性且风险很高。他接受了使用重叠PED对破裂的VFA进行血管内治疗。以套叠方式放置了5个PED,以重建左椎动脉和基底动脉的受累部分。在常规脑血管造影期间还发现右侧椎动脉有一个额外的2毫米泡状动脉瘤,并用另外一个PED进行了治疗。术后患者神经功能保持完好。继续给予他阿司匹林和氯吡格雷。3个月后的随访磁共振成像显示支架通畅,没有任何缺血改变的迹象。6个月后的随访常规脑血管造影显示VFA血栓形成以及椎基底系统重建。患者临床状况良好。在某些情况下,使用PED的血管内治疗方法对于破裂性VFA可能是一种安全有效的治疗选择。