然而他们并未这样做：基于NAOMI研究幸存者经历的建议及行动呼吁。
Yet they failed to do so: recommendations based on the experiences of NAOMI research survivors and a call for action.
作者信息
Boyd Susan
出版信息
Harm Reduct J. 2013 Apr 18;10:6. doi: 10.1186/1477-7517-10-6.
Abstract
BACKGROUND
This article highlights the experiences of a unique group. In January 2011, Dave Murray organized a group of participants from the North American Opiate Medication Initiative (NAOMI) heroin-assisted treatment clinical trials from 2005 to 2008 in the Downtown Eastside of Vancouver (DTES), B.C., Canada. The NAOMI Patients Association (NPA) is an independent group that currently meets every Saturday in the DTES. Currently, all members of the NPA are former participants in the heroin stream of the clinical trial. The NPA offers support, education, and advocacy to its members.
METHODS
Drawing on brainstorming sessions and focus groups that were conducted in the summer of 2011, this paper highlights the experiences of NPA members in their own words.
RESULTS
The findings provide a lens to understand how becoming a research subject for the NAOMI trial impacted the lives of NPA members, both positive and negative. The NPA members discuss ethics, consent, recommendations for future HAT programs and studies, and ongoing advocacy.
摘要
背景
本文重点介绍了一个独特群体的经历。2011年1月，戴夫·默里组织了一群来自北美阿片类药物治疗倡议（NAOMI）的参与者，他们参与了2005年至2008年在加拿大不列颠哥伦比亚省温哥华市中心东区（DTES）进行的海洛因辅助治疗临床试验。NAOMI患者协会（NPA）是一个独立团体，目前每周六在DTES聚会。目前，NPA的所有成员都是该临床试验海洛因治疗组的前参与者。NPA为其成员提供支持、教育和宣传。
方法
本文借鉴了2011年夏天举行的头脑风暴会议和焦点小组讨论的内容，用NPA成员自己的话重点介绍了他们的经历。
结果
研究结果为理解成为NAOMI试验的研究对象如何对NPA成员的生活产生积极和消极影响提供了一个视角。NPA成员讨论了伦理、同意、对未来海洛因辅助治疗项目和研究的建议以及持续的宣传活动。
相似文献
1
Yet they failed to do so: recommendations based on the experiences of NAOMI research survivors and a call for action.
Harm Reduct J. 2013 Apr 18;10:6. doi: 10.1186/1477-7517-10-6.
2
Telling our stories: heroin-assisted treatment and SNAP activism in the Downtown Eastside of Vancouver.
Harm Reduct J. 2017 May 18;14(1):27. doi: 10.1186/s12954-017-0152-3.
3
A heroin prescription trial: case studies from Montreal and Vancouver on crime and disorder in the surrounding neighbourhoods.
Int J Drug Policy. 2010 Jan;21(1):28-35. doi: 10.1016/j.drugpo.2009.04.003. Epub 2009 May 15.
4
The effect of motivational status on treatment outcome in the North American Opiate Medication Initiative (NAOMI) study.
Drug Alcohol Depend. 2010 Sep 1;111(1-2):161-5. doi: 10.1016/j.drugalcdep.2010.03.019. Epub 2010 May 26.
5
Is there a need for heroin substitution treatment in Vancouver's Downtown Eastside? Yes there is, and in many other places too.
Can J Public Health. 2011 Mar-Apr;102(2):87-9. doi: 10.1007/BF03404153.
6
Is there a need for heroin substitution treatment in Vancouver's Downtown Eastside?
Can J Public Health. 2011 Mar-Apr;102(2):84-6. doi: 10.1007/BF03404152.
7
"SALOME gave my dignity back": the role of randomized heroin trials in transforming lives in the Downtown Eastside of Vancouver, Canada.
Int J Qual Stud Health Well-being. 2014 Mar 13;9:23698. doi: 10.3402/qhw.v9.23698. eCollection 2014.
8
The North American Opiate Medication Initiative (NAOMI): profile of participants in North America's first trial of heroin-assisted treatment.
J Urban Health. 2008 Nov;85(6):812-25. doi: 10.1007/s11524-008-9312-9. Epub 2008 Aug 29.
9
Scientific and political challenges in North America's first randomized controlled trial of heroin-assisted treatment for severe heroin addiction: rationale and design of the NAOMI study.
Clin Trials. 2009 Jun;6(3):261-71. doi: 10.1177/1740774509105222.
10
The Swiss heroin trials. Trial is needed comparing decriminalisation of heroin with existing policy of prohibition.
BMJ. 1998 Oct 10;317(7164):1011; author reply 1011-2.
引用本文的文献
1
Barriers and facilitators to injectable opioid agonist treatment engagement within a structural vulnerability context: a qualitative study of patient experiences in Vancouver, Canada.
Harm Reduct J. 2025 Jul 4;22(1):116. doi: 10.1186/s12954-025-01262-4.
2
(Epistemic) Injustice and Resistance in Canadian Research Ethics Governance.
Ethics Hum Res. 2025 Jan-Feb;47(1):2-19. doi: 10.1002/eahr.60004.
3
Vancouver's Alcohol Knowledge Exchange: lessons learned from creating a peer-involved alcohol harm reduction strategy in Vancouver's Downtown Eastside.
Harm Reduct J. 2023 Jul 26;20(1):93. doi: 10.1186/s12954-023-00838-2.
4
Community-Engaged Research Ethics Training (CERET): developing accessible and relevant research ethics training for community-based participatory research with people with lived and living experience using illicit drugs and harm reduction workers.
Harm Reduct J. 2023 Jul 6;20(1):86. doi: 10.1186/s12954-023-00818-6.
5
'This is hardcore': a qualitative study exploring service users' experiences of Heroin-Assisted Treatment (HAT) in Middlesbrough, England.
Harm Reduct J. 2023 May 12;20(1):66. doi: 10.1186/s12954-023-00785-y.
6
Applicability of a national strategy for patient-oriented research to people who use(d) substances: a Canadian experience.
Res Involv Engagem. 2022 May 24;8(1):22. doi: 10.1186/s40900-022-00351-z.
7
An age-based analysis of nonmedical prescription opioid use among people who use illegal drugs in Vancouver, Canada.
Subst Abuse Treat Prev Policy. 2018 Nov 27;13(1):41. doi: 10.1186/s13011-018-0180-3.
8
Supervised Injectable Opioid Treatment for the Management of Opioid Dependence.
Drugs. 2018 Sep;78(13):1339-1352. doi: 10.1007/s40265-018-0962-y.
9
Activism and scientific research: 20 years of community action by the Vancouver area network of drug users.
Subst Abuse Treat Prev Policy. 2018 May 22;13(1):18. doi: 10.1186/s13011-018-0158-1.
10
Telling our stories: heroin-assisted treatment and SNAP activism in the Downtown Eastside of Vancouver.
Harm Reduct J. 2017 May 18;14(1):27. doi: 10.1186/s12954-017-0152-3.
本文引用的文献
1
From risky places to safe spaces: Re-assembling spaces and places in Vancouver's Downtown Eastside.
Health Place. 2019 Sep;59:102164. doi: 10.1016/j.healthplace.2019.102164. Epub 2019 Aug 2.
2
How well do international drug conventions protect public health?
Lancet. 2012 Jan 7;379(9810):84-91. doi: 10.1016/S0140-6736(11)61423-2.
3
Heroin-assisted treatment in the Netherlands: History, findings, and international context.
Eur Neuropsychopharmacol. 2010 Apr;20 Suppl 2:S105-58. doi: 10.1016/S0924-977X(10)70001-8.
4
Women's health and use of crack cocaine in context: structural and 'everyday' violence.
Int J Drug Policy. 2010 Jul;21(4):321-9. doi: 10.1016/j.drugpo.2009.12.008. Epub 2010 Feb 8.
5
NAOMI: The trials and tribulations of implementing a heroin assisted treatment study in North America.
Harm Reduct J. 2009 Jan 21;6:2. doi: 10.1186/1477-7517-6-2.
6
Opportunities to learn and barriers to change: crack cocaine use in the Downtown Eastside of Vancouver.
Harm Reduct J. 2008 Nov 17;5:34. doi: 10.1186/1477-7517-5-34.
7
Burden of HIV infection among aboriginal injection drug users in Vancouver, British Columbia.
Am J Public Health. 2008 Mar;98(3):515-9. doi: 10.2105/AJPH.2007.114595. Epub 2008 Jan 30.
8
Policy makers ignoring science and scientists ignoring policy: the medical ethical challenges of heroin treatment.
Harm Reduct J. 2006 May 2;3:16. doi: 10.1186/1477-7517-3-16.
9
Drastic elevations in mortality among female injection drug users in a Canadian setting.
AIDS Care. 2006 Feb;18(2):101-8. doi: 10.1080/09540120500159292.
10
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.
J Int Bioethique. 2004 Mar;15(1):124-9.
Zotero 插件