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对切尔诺贝利组织库中登记的乌克兰受试者个体甲状腺剂量的重建。

Reconstruction of individual thyroid doses to the Ukrainian subjects enrolled in the Chernobyl Tissue Bank.

作者信息

Likhtarov I, Thomas G, Kovgan L, Masiuk S, Chepurny M, Ivanova O, Gerasymenko V, Tronko M, Bogdanova T, Bouville A

机构信息

State Institution 'National Research Centre for Radiation Medicine of the National Academy of Medical Sciences of Ukraine', 53 Melnykova Street, Kyiv 04050, Ukraine.

出版信息

Radiat Prot Dosimetry. 2013 Oct;156(4):407-23. doi: 10.1093/rpd/nct096. Epub 2013 Apr 17.

DOI:10.1093/rpd/nct096
PMID:23595409
Abstract

The Chernobyl Tissue Bank (CTB) is an organisation that collects and stores samples of tumoral thyroid tissue obtained from Ukrainian and Russian subjects who were treated surgically for a thyroid cancer and had been exposed to (131)I from the Chernobyl accident. By 2012, the CTB had collected specimens of thyroid tissue from 2267 residents of Ukraine for the purpose of radiation research. Arithmetic mean thyroid doses and uncertainties have been estimated for all but 24 subjects for whom residence at the time of exposure was not found. The subjects have been classified into six groups or sub-groups according to the type of dosimetry-related information that is available for each of them. Excluding the 325 subjects with negligible radiation exposure, the arithmetic mean of the thyroid dose over all subjects is estimated as 0.4 Gy, with individual values ranging from <1 mGy to 13 Gy. The uncertainties in the individual thyroid dose estimates, characterised by the geometric standard deviations of their probability distributions, range from 1.3 to 8.7, with an arithmetic mean of 3.2.

摘要

切尔诺贝利组织库(CTB)是一个收集和储存肿瘤性甲状腺组织样本的机构,这些样本取自因甲状腺癌接受手术治疗且曾在切尔诺贝利事故中受到¹³¹I照射的乌克兰和俄罗斯患者。截至2012年,CTB已为辐射研究目的收集了2267名乌克兰居民的甲状腺组织标本。除24名暴露时居住地未找到的受试者外,已对所有受试者的算术平均甲状腺剂量和不确定性进行了估计。根据每个受试者可获得的剂量测定相关信息类型,将受试者分为六组或亚组。排除325名辐射暴露可忽略不计的受试者后,所有受试者的甲状腺剂量算术平均值估计为0.4 Gy,个体值范围从<1 mGy至13 Gy。个体甲状腺剂量估计值的不确定性以其概率分布的几何标准差表示,范围从1.3至8.7,算术平均值为3.2。

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