INRA, Laboratoire des Interactions Plantes-Microorganismes, UMR441 Castanet-Tolosan, France ; CNRS, Laboratoire des Interactions Plantes-Microorganismes, UMR2594 Castanet-Tolosan, France.
Front Plant Sci. 2013 Apr 11;4:98. doi: 10.3389/fpls.2013.00098. eCollection 2013.
Transcriptional regulation in host cells plays a crucial role in the establishment of plant defense and associated cell death in response to pathogen attack. Here, we review our current knowledge of the transcriptional control of plant defenses with a focus on the MYB family of transcription factors (TFs). Within this family, the Arabidopsis MYB protein AtMYB30 is a key regulator of plant defenses and one of the best characterized MYB regulators directing defense-related transcriptional responses. The crucial role played by AtMYB30 in the regulation of plant disease resistance is underlined by the finding that AtMYB30 is targeted by the Xanthomonas type III effector XopD resulting in suppression of AtMYB30-mediated plant defenses. Moreover, the function of AtMYB30 is also tightly controlled by plant cells through protein-protein interactions and post-translational modifications (PTMs). AtMYB30 studies highlight the importance of cellular dynamics for defense-associated gene regulation in plants. Finally, we discuss how AtMYB30 and other MYB TFs mediate the interplay between disease resistance and other stress responses.
宿主细胞中的转录调控在植物防御的建立以及对病原体攻击的相关细胞死亡中起着至关重要的作用。在这里，我们回顾了我们目前对植物防御的转录控制的了解，重点是 MYB 家族的转录因子 (TFs)。在这个家族中，拟南芥 MYB 蛋白 AtMYB30 是植物防御的关键调节剂，也是指导与防御相关的转录反应的最具特征的 MYB 调节剂之一。AtMYB30 在植物抗病性调节中的关键作用是由以下发现所强调的：XopD 是黄单胞菌 III 型效应因子，靶向 AtMYB30，导致 AtMYB30 介导的植物防御被抑制。此外，AtMYB30 的功能也通过蛋白质-蛋白质相互作用和翻译后修饰 (PTMs) 受到植物细胞的严格控制。AtMYB30 的研究强调了细胞动力学对植物中与防御相关的基因调控的重要性。最后，我们讨论了 AtMYB30 和其他 MYB TF 如何介导抗病性和其他应激反应之间的相互作用。
