Otaki Yuzo, Homma Kiyoaki, Nawata Yoshitakata, Imaizumi Kazuomi, Arai Shigeru
Yuzo Otaki, Kiyoaki Homma, Yoshitakata Nawata, Department of Therapeutic Endoscopy, Nihonkai General Hospital, Yamagata 998-0828, Japan.
World J Gastrointest Endosc. 2013 Apr 16;5(4):197-200. doi: 10.4253/wjge.v5.i4.197.
Duodenal carcinoids are a rare form of neuroendocrine tumors, and tend to invade the submucosa during the early stage. Endoscopic treatment is generally recommended for duodenal carcinoids less than 10 mm in diameter. Although a few reports have described the use of endoscopic resection of duodenal carcinoids, there are no published studies on endoscopic mucosal resection with circumferential mucosal incision (EMR-CMI). We performed EMR-CMI for 5 cases of duodenal carcinoids in the duodenal bulb. The mean tumor diameter was 4.6 ± 1.8 mm. Although all of the tumors were located in the submucosa, R0 resection was performed without complication in each case. EMR-CMI may thus be a safe and effective treatment for duodenal carcinoids less than 10 mm in diameter.
十二指肠类癌是一种罕见的神经内分泌肿瘤,早期往往侵犯黏膜下层。对于直径小于10毫米的十二指肠类癌,一般建议采用内镜治疗。虽然有少数报告描述了十二指肠类癌的内镜切除,但尚无关于内镜下环形黏膜切开黏膜切除术(EMR-CMI)的发表研究。我们对5例十二指肠球部的十二指肠类癌进行了EMR-CMI。肿瘤平均直径为4.6±1.8毫米。尽管所有肿瘤均位于黏膜下层,但每例均实现了R0切除,且无并发症发生。因此,EMR-CMI可能是治疗直径小于10毫米的十二指肠类癌的一种安全有效的方法。