Endocrinology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
J Tradit Chin Med. 2013 Feb;33(1):27-33. doi: 10.1016/s0254-6272(13)60096-5.
Sui Zheng Shi Liang strategy (regulating prescription dosage with different syndromes) is an important part of syndrome differentiation and treatment in Traditional Chinese Medicine (TCM). Questionnaires were given to doctors and patients to study the essential factors (indicators and timing) of Sui Zheng Shi Liang strategy in the treatment process of type 2 diabetes (T2DM).
Two questionnaires were designed for diabetes patients and their doctors. The questionnaires included the most important indicators for determining the patient's condition, the ability of TCM in treating T2DM, the length of time it takes forTCM to be effective, and when to adjust the prescription dosage. The frequency of answers was calculated, summarized, and analyzed after the survey.
Twenty questionnaires from doctors and 90 questionnaires from patients were included in the analysis. Doctors and patients recognized that TCM could decrease blood glucose, improve syndromes, and delay complications. Doctors were mainly concerned about glycosylated hemoglobin, while the patients were concerned about fasting plasma glucose for determining whether treatment was effective. Doctors also paid attention to changes in blood sugar and syndromes 2 weeks after medication was given as the indication to adjust the prescription dosage, while patients were concerned about these factors in 4 weeks. The prescription should be regulated when there are side effects or the medication is ineffective.
The essential factor in the treatment process of T2DM in Sui Zheng Shi Liang strategy is that if fasting blood glucose level did not decrease after 4 weeks of treatment, the Chinese medicine prescription should be adjusted.
随证试量策略（根据不同证型调整方剂剂量）是中医辨证论治的重要组成部分。通过对医生和患者进行问卷调查，研究 2 型糖尿病（T2DM）治疗过程中随证试量策略的关键要素（指标和时机）。
设计了针对糖尿病患者及其医生的两份问卷。问卷包括确定患者病情的最重要指标、中医治疗 T2DM 的能力、中医起效所需的时间以及何时调整处方剂量。调查后对答案的频率进行计算、总结和分析。
纳入分析的医生问卷 20 份，患者问卷 90 份。医生和患者均认为中医可以降低血糖、改善症状、延缓并发症。医生主要关注糖化血红蛋白，而患者则关注空腹血糖来判断治疗是否有效。医生还关注用药 2 周后血糖和症状的变化作为调整处方剂量的指征，而患者则关注 4 周后的这些因素。当出现副作用或药物无效时，应调整处方。
随证试量策略治疗 T2DM 的关键要素是，如果治疗 4 周后空腹血糖水平没有下降，应调整中药方剂。
