Department of Endocrinology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
Graduate College, Beijing University of Traditional Chinese Medicine, Beijing 100029, China.
J Diabetes Res. 2019 Nov 5;2019:3054213. doi: 10.1155/2019/3054213. eCollection 2019.
Diabetes mellitus (DM) belongs to the progressive and irreversible disease. With the development of the disease, the function of beta cells declines significantly. Current treatments cannot reverse the course of the disease. The role of traditional Chinese medicine (TCM) in the DM treatment has been recognized widely, while there are few long-term observation reports. In this study, we introduced a case of DM treated by classical prescription alone for 10 years, which would provide the reference for clinical practice.
A 64-year-old male complained of a 2-month history of dry mouth, frequent urination, and blurred vision and found increased blood glucose for 3 days. The patient's glycated hemoglobin was 14.2%, fasting plasma glucose fluctuated at 12-15 mmol/L, and urinary albumin excretion rate (UAER) was 32.9 g/min. The male was treated with 10 years of continuous classical prescription alone. After 3 months of TCM treatment, the patient's blood glucose level decreased significantly and blurred vision symptoms improved. With continued TCM treatment, his UAER normalized. Subsequently, he continued outpatient consultation, and his TCM prescription was adjusted according to clinical symptoms. After 10 years of continuous TCM treatment, his blood glucose remained stable, urinary microalbumin quantitation showed no abnormalities, and blurred vision disappeared.
This case provides specific treatment plans and effective references for long-term control of blood glucose, prevention and treatment of diabetes complications, delay of disease progression, and protection of impaired islet function in the treatment of diabetes with TCM. TCM may become a meaningful alternative DM treatment in the future.
糖尿病（DM）属于进展性和不可逆性疾病。随着疾病的发展，β细胞功能显著下降。目前的治疗方法无法逆转疾病进程。中医药（TCM）在 DM 治疗中的作用已得到广泛认可，但长期观察报告较少。本研究介绍了 1 例单独使用经典方剂治疗 10 年的 DM 病例，为临床实践提供参考。
一名 64 岁男性因口干、尿频和视力模糊 2 个月就诊，发现血糖升高 3 天。患者糖化血红蛋白为 14.2%，空腹血糖波动在 12-15mmol/L 之间，尿白蛋白排泄率（UAER）为 32.9μg/min。该男性接受了 10 年连续单独经典方剂治疗。TCM 治疗 3 个月后，患者血糖水平显著下降，视力模糊症状改善。继续 TCM 治疗后，UAER 恢复正常。随后，他继续门诊就诊，根据临床症状调整 TCM 处方。经过 10 年连续 TCM 治疗，他的血糖保持稳定，尿微量白蛋白定量无异常，视力模糊消失。
本病例为长期控制血糖、预防和治疗糖尿病并发症、延缓疾病进展、保护受损胰岛功能的 TCM 治疗糖尿病提供了具体的治疗方案和有效参考。TCM 可能成为未来有意义的 DM 治疗替代方法。
