Ossenkopp K P, Ossenkopp M D
Department of Psychology, University of Western Ontario, London, Canada.
Physiol Behav. 1990 Mar;47(3):467-70. doi: 10.1016/0031-9384(90)90110-p.
The presence of motion sickness in albino guinea pigs (Cavia porcellus) was examined by using a conditioned taste aversion (CTA) as an index. Eighteen animals were divided into three groups. One group received four pairings of a novel 0.15% saccharin solution followed by 20 min of body rotation at 70 rpm (on a schedule of 15 sec on and 5 sec off). Another group received four pairings of the saccharin solution followed by exposure to sham rotation. The third group experienced the rotation procedure following access to water. The group receiving the rotation procedure contingent on presentation of the novel saccharin taste exhibited a conditioned aversion to this fluid (relative to the control groups) over days of acquisition (p less than 0.01), which subsequently dissipated when rotation was no longer contingent on the presentation of the saccharin solution (extinction). These data thus demonstrate the presence of motion sickness in guinea pigs when CTA is used as an index.
以条件性味觉厌恶（CTA）为指标，对白化豚鼠（豚鼠）的晕动病情况进行了检查。18只动物被分为三组。一组接受了四次0.15%新型糖精溶液配对，随后以70转/分钟的速度进行20分钟的身体旋转（开启15秒，关闭5秒的模式）。另一组接受了四次糖精溶液配对，随后进行假旋转。第三组在接触水后经历旋转程序。在获得糖精溶液的过程中，接受与新型糖精味道呈现相关的旋转程序的组对这种液体表现出条件性厌恶（相对于对照组）（p小于0.01），当旋转不再与糖精溶液的呈现相关时（消退），这种厌恶随后消失。因此，这些数据表明，当以CTA为指标时，豚鼠存在晕动病。
