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豚鼠实验性晕动病期间的主动姿势控制

Active posture control during experimental motion sickness in guinea-pigs.

作者信息

Ikeda T, Takahashi M

机构信息

Department of Otolaryngology, Yamaguchi University School of Medicine, Japan.

出版信息

Acta Otolaryngol. 1997 Nov;117(6):815-8. doi: 10.3109/00016489709114206.

DOI:10.3109/00016489709114206
PMID:9442819
Abstract

This study evaluated active posture control in guinea-pigs under motion sickness stimulation. Twelve guinea-pigs, which received training to stay on a moving perch, were divided into two groups: a motion sickness stimulation group and a control group. The motion sickness group was given a combined stimulation of turntable rotation and optokinetic drum rotation, and the control group was given turntable stimulation alone. Motion sickness was evaluated by conditioned taste aversion to saccharin solution. Active posture control was evaluated by the angle of nose tip displacement and the staying duration (length of time that guinea-pigs stayed on the turntable). The consumption of saccharin solution increased in the control group but did not increase in the motion sickness group. The motion sickness group showed a significant increase in the mean angle of nose tip displacement and a significant decrease in the staying duration on the turntable. These results indicate that active posture control was disturbed by motion sickness stimulation.

摘要

本研究评估了晕动病刺激下豚鼠的主动姿势控制。十二只接受过在移动栖木上停留训练的豚鼠被分为两组:晕动病刺激组和对照组。晕动病组接受转盘旋转和视动鼓旋转的联合刺激,对照组仅接受转盘刺激。通过对糖精溶液的条件性味觉厌恶来评估晕动病。通过鼻尖位移角度和停留时间(豚鼠在转盘上停留的时间长度)来评估主动姿势控制。对照组中糖精溶液的消耗量增加,而晕动病组中未增加。晕动病组的鼻尖平均位移角度显著增加,在转盘上的停留时间显著减少。这些结果表明,主动姿势控制受到晕动病刺激的干扰。

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