Remy G
Service de médecine interne et des maladies infectieuses, hôpital Robert-Debré, Reims.
Rev Prat. 1990 May 11;40(14):1285-8.
Infection of the prostatic gland tissue is frequent, affecting from 4 to 5% of men according to anatomical studies. The classical distinction between acute and chronic prostatitis still too often suggests different diseases, whereas chronic prostatitis in fact is the clinical expression of an initial acute or subacute infection for lack of diagnosis and therefore of an appropriate and sufficiently prolonged treatment. In both acute and chronic prostatitis the pathogens are the same: E. coli at all ages, organisms causing urethritis in young men, Gram-negative and often multiresistant bacilli in iatrogenic infections. Fluoroquinolones, which are active against most of these bacteria and are present in high concentrations in the prostate, are for the moment among the most effective antibacterial agents. But unless they are prescribed at an early stage and for long periods prostatitis may remain a desperately chronic disease.
前列腺组织感染很常见，解剖学研究表明，4%至5%的男性会受到影响。急性前列腺炎和慢性前列腺炎之间的传统区分常常仍暗示着不同的疾病，而事实上，慢性前列腺炎是初始急性或亚急性感染因缺乏诊断以及因此缺乏适当且足够长时间治疗的临床表型。在急性和慢性前列腺炎中，病原体是相同的：各年龄段均以大肠杆菌为主，年轻男性中为引起尿道炎的病原体，医源性感染中为革兰氏阴性且往往多重耐药的杆菌。氟喹诺酮类药物对这些细菌中的大多数都有活性，且在前列腺中浓度很高，目前是最有效的抗菌药物之一。但除非早期且长时间给药，前列腺炎可能会一直是一种极为棘手的慢性病。
