Apollonio G, Dederding J P, Bosson R, Baumann R, Loup R, Girard L, Miazza B, de Peyer R, Loizeau E
Département de médecine, Hôpital cantonal universitaire, Genève.
Schweiz Med Wochenschr. 1990 Jun 2;120(22):830-2.
Of 69 patients with non-cardiac chest pain, one third had abnormal esophageal motility as evidenced by basal esophageal manometry. 8 patients (12%) reported chest pain during a provocation test (edrophonium). While this pain seemed similar to the spontaneous chest pain described by 7 patients, it was not associated with manometric changes in 30% of these cases. The causal relationship between disorders of esophageal motility and non-cardiac chest pain has still to be confirmed, and caution must be exercised in interpreting edrophonium tests.
在69例非心源性胸痛患者中,三分之一的患者食管基础测压显示食管动力异常。8例患者(12%)在激发试验(依酚氯铵)期间报告胸痛。虽然这种疼痛似乎与7例患者描述的自发性胸痛相似,但在这些病例中有30%与测压变化无关。食管动力障碍与非心源性胸痛之间的因果关系仍有待证实,在解释依酚氯铵试验时必须谨慎。