[乳腺癌中的巨球蛋白家族蛋白]
[Macroglobulin family proteins in breast cancer].
作者信息
Promzeleva N V, Zorina V N, Zorin N A
出版信息
Vopr Onkol. 2012;58(5):688-90.
PMID:23600290
Abstract
Determined serum levels of alpha-2-macroglobulin (a2-MG) and pregnancy-associate alpha-2-glycoprotein (a2-PAG) in 98 breast cancer patients stage I-IV prior to the special antitumor treatment. Statistically significant negative correlative dependence of the a2-PAG in the blood and lifetime of patients is proved. We believe that the definition of pre-treatment level of a serum a2-MG and a2-PAG concentrations for patients with breast cancer, can be used as an additional predictor of life expectancy.
摘要
在98例I-IV期乳腺癌患者接受特殊抗肿瘤治疗之前，测定其血清α-2-巨球蛋白（a2-MG）和妊娠相关α-2-糖蛋白（a2-PAG）水平。已证实血液中a2-PAG与患者生存期之间存在统计学上显著的负相关。我们认为，测定乳腺癌患者治疗前血清a2-MG和a2-PAG浓度水平，可作为预期寿命的额外预测指标。
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