[前列腺癌患者中疱疹病毒和人乳头瘤病毒对前列腺的感染]
[Infection of the prostate by herpesviruses and HPV in patients with prostate cancer].
作者信息
Samsonov R B, Klochkova T G, Evtushenko V I
出版信息
Vopr Onkol. 2012;58(6):795-9.
The exploration of the presence of the HCMV, EBV, HHV8 and HPV-infection in the prostatic tissue of the prostate cancer patients was conducted. The methods of PCR and in situ hybridization (ISH) were used and the results were compared. Authors revealed high degree of virus infection in prostate. Using of PCR and ISH resulted in following frequencies of the viruses in prostate tissue: HCMV-87 and 77%, EBV-53 and 54%, HHV8--0 and 50%, HPV--0 and 23%. The question of the nature of discrepancies is discussed.
对前列腺癌患者前列腺组织中是否存在人巨细胞病毒（HCMV）、爱泼斯坦-巴尔病毒（EBV）、人疱疹病毒8型（HHV8）和人乳头瘤病毒（HPV）感染进行了探索。采用聚合酶链反应（PCR）和原位杂交（ISH）方法，并对结果进行比较。作者发现前列腺中病毒感染程度较高。使用PCR和ISH检测前列腺组织中病毒的频率如下：HCMV分别为87%和77%，EBV分别为53%和54%，HHV8分别为0和50%，HPV分别为0和23%。文中讨论了差异性质的问题。
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