Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.
J Diabetes. 2013 Sep;5(3):254-7. doi: 10.1111/1753-0407.12052. Epub 2013 May 29.
The development of a closed-loop "artificial pancreas" would be a welcome advance for both endocrinologists and diabetic patients struggling to attain near normal glycemic control. While great strides in automatically controlling blood sugar in the fasting, sedentary state have been made through complex mathematical modeling, management of blood sugar excursions due to food and exercise have been more problematic. An artificial pancreas is not feasible at this time because of limitations inherent in the currently available technology.
闭环“人工胰腺”的开发将受到内分泌学家和努力实现接近正常血糖控制的糖尿病患者的欢迎。虽然通过复杂的数学模型在空腹、静坐状态下自动控制血糖方面取得了巨大进展,但由于食物和运动导致的血糖波动管理更为困难。由于目前可用技术的固有限制,人工胰腺目前还不可行。