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213例儿童眼肿瘤的病理分析

[The pathological analysis of 213 children with ocular tumor].

作者信息

Wei Qiu-cai, Li Xiao-hua, Hao Yuan-rui

机构信息

Henan Eye Institute, Henan Key Laboratory of Keratonosus, Zhengzhou 450003, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2013 Jan;49(1):37-40.

PMID:23601464
Abstract

OBJECTIVE

To analyze the pathological classification of ocular tumor in children.

METHODS

213 cases (214 eyes) of ocular tumor in children below 14 years old between January 2001 and December 2007 in Henan Eye Institute were reviewed retrospectively, the pathological classification were made according to the location and nature of the tumor.

RESULTS

There were 17 eyes (7.94%) of 214 eyes with benign tumor of eyelid, the leading two tumor were 4 eyes with cyst, in which 1 eye with epidermoid cyst and 3 eyes with dermoid cyst were included, and 3 eyes with squamous papilloma. There were 84 eyes (39.25%) of 214 eyes with conjunctival and corneal tumor, 1 eye with intraepithelial tumor was found, other tumors were all benign tumor, the leading three tumors were corneal dermoid (64 eyes), conjunctival nevus (10 eyes) and squamous papilloma (4 eyes). There were 73 eyes (34.11%) with intraocular tumor including 66 eyes (90.41%) with retinoblastoma, 6 eyes (8.22%) with iris cyst and 1 eye (1.37%) with iris melanoma. Of 38 eyes of orbital tumor, cyst (16 eyes), vascular hamartoma (7 eyes) and inflammatory pseudotumor (4 eyes) were the most common benign tumors, there were 3 eyes (7.89%) with orbital extension of retinoblastoma and 2 eyes (5.26%) with rhabdosarcoma. There were 2 eyes with scleral tumor, including 1 eye with scleral bony choristoma and 1 eye with congenital scleral cyst. Altogether, there are 135 eyes (63.08%) with benign tumor and 79 eyes (36.92%) with malignant tumors.

CONCLUSIONS

Most children's ocular tumors are congenital and embryonic tumors. Retinoblastoma is the most common malignant ocular tumor in children, then is corneal dermoid.

摘要

目的

分析儿童眼部肿瘤的病理分类。

方法

回顾性分析2001年1月至2007年12月在河南省眼科研究所就诊的14岁以下儿童眼部肿瘤213例(214眼),根据肿瘤的部位及性质进行病理分类。

结果

214眼中眼睑良性肿瘤17眼(7.94%),前两位的肿瘤为囊肿4眼,其中表皮样囊肿1眼、皮样囊肿3眼,鳞状乳头瘤3眼。结膜及角膜肿瘤84眼(39.25%),上皮内肿瘤1眼,其余均为良性肿瘤,前三位的肿瘤为角膜皮样瘤(64眼)、结膜痣(10眼)和鳞状乳头瘤(4眼)。眼内肿瘤73眼(34.11%),其中视网膜母细胞瘤66眼(90.41%),虹膜囊肿6眼(8.22%),虹膜黑色素瘤1眼(1.37%)。眼眶肿瘤38眼中,囊肿(16眼)、血管性错构瘤(7眼)和炎性假瘤(4眼)是最常见的良性肿瘤,视网膜母细胞瘤眼眶蔓延3眼(7.89%),横纹肌肉瘤2眼(5.26%)。巩膜肿瘤2眼,其中巩膜骨化性迷离瘤1眼,先天性巩膜囊肿1眼。良性肿瘤共135眼(63.08%),恶性肿瘤79眼(36.92%)。

结论

儿童眼部肿瘤多为先天性及胚胎性肿瘤。视网膜母细胞瘤是儿童最常见的恶性眼部肿瘤,其次是角膜皮样瘤。

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