Department of Medicine, Division of Infectious Diseases, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Diagn Microbiol Infect Dis. 2013 Jul;76(3):382-4. doi: 10.1016/j.diagmicrobio.2013.03.015. Epub 2013 Apr 18.
The significance of candiduria remains unclear. We correlated Candida albicans candidemia with candiduria by molecular genotyping. 33 pairs of concurrent blood and urine C. albicans isolates from 31 adult (≥ 18 years) were genotyped with infrequent-restriction-site PCR. The molecular concordance rates of three major genotypes were 100% for I, 82% for II, and 71% for III. The molecular concordance between concurrent C. albicans candidemia and candiduria was frequent. Our findings substantiate the importance of candiduria in appropriate clinical context as the majority of our patients were from intensive care units.
尿白念珠菌的意义仍不明确。我们通过分子基因分型将白念珠菌血症与尿白念珠菌相关联。对 31 名成人(≥18 岁)的 33 对同时存在的血液和尿液白念珠菌分离株进行了少见限制性内切酶 PCR 基因分型。三种主要基因型的分子一致性率分别为 I 型 100%、II 型 82%和 III 型 71%。同时存在的白念珠菌血症和尿白念珠菌之间的分子一致性很常见。我们的发现证实了在适当的临床背景下尿白念珠菌的重要性,因为我们的大多数患者都来自重症监护病房。