急性髓细胞白血病患者因眼部受累而引发致命性播散性 prolificans 枝孢霉感染。

Fatal disseminated Scedosporium prolificans infection initiated by ophthalmic involvement in a patient with acute myeloblastic leukemia.

机构信息

Institute for Applied Ophthalmobiology (IOBA), University of Valladolid, 47011 Valladolid, Spain.

出版信息

Diagn Microbiol Infect Dis. 2013 Jul;76(3):375-8. doi: 10.1016/j.diagmicrobio.2013.03.006. Epub 2013 Apr 18.

DOI:10.1016/j.diagmicrobio.2013.03.006

Abstract

Scedosporium prolificans is an opportunistic saprophytic fungus that rapidly disseminates and is intrinsically resistant to currently available antifungal drugs. We report a fatal case of disseminated S. prolificans infection that started with orbital and ocular involvement in a patient with secondary acute myeloblastic leukemia.

摘要

枝顶孢属是一种机会性腐生真菌，具有快速传播和固有抗药性的特点，目前可用的抗真菌药物对此类真菌的治疗效果不佳。我们报告了一例继发于急性髓系白血病的致命性播散性枝顶孢属感染病例，该患者最初表现为眼眶和眼部受累。