Laboratório de Pesquisa em Micologia Aplicada, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Arch Microbiol. 2023 May 15;205(6):236. doi: 10.1007/s00203-023-03536-6.
Ocular fungal infections annually affect more than one million individuals worldwide. The management of these infections is problematic, mainly due to the limited availability of effective antifungal agents. Thus, ocular infections are increasingly recognized as important causes of morbidity and blindness, especially keratitis and endophthalmitis. Thus, this review aims to demonstrate the importance of fungal eye infections through the description of the main related aspects, with emphasis on the treatment of these infections. For this purpose, a search for scientific articles was conducted in databases, such as Medline, published from 2000 onwards, addressing important aspects involving fungal eye infections. In addition, this work highlighted the limited therapeutic arsenal available and the severity associated with these infections. Thus, highlighting the importance of constantly updating knowledge about these pathologies, as it contributes to agility in choosing the available and most appropriate therapeutic alternatives, aiming at positive and minimally harmful results for that particular patient.
全球每年有超过 100 万人受到眼部真菌感染的影响。这些感染的治疗存在问题，主要是因为有效的抗真菌药物有限。因此，眼部感染越来越被认为是发病率和失明的重要原因，特别是角膜炎和眼内炎。因此，本综述旨在通过描述主要相关方面，强调这些感染的治疗，来展示真菌性眼部感染的重要性。为此，在 Medline 等数据库中搜索了自 2000 年以来发表的涉及真菌性眼部感染的重要方面的科学文章。此外，本工作还强调了现有治疗手段的局限性和这些感染的严重性。因此，突出了不断更新对这些疾病的认识的重要性，因为这有助于在选择现有最合适的治疗方案时更加灵活，从而为特定患者带来积极和最小的伤害结果。
