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猫乳腺肿瘤:大小很关键,因此早期干预可挽救生命。

Mammary tumours in the cat: size matters, so early intervention saves lives.

作者信息

Morris Joanna

机构信息

School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Bearsden, Glasgow G61 1QH, UK.

出版信息

J Feline Med Surg. 2013 May;15(5):391-400. doi: 10.1177/1098612X13483237.

Abstract

PRACTICAL RELEVANCE

Mammary tumours are among the most common neoplasms in both cats and dogs, but the prevalence of malignant histological types is far higher in cats (ratio of malignant:benign is at least 4:1).

CLINICAL CHALLENGES

The more aggressive nature of mammary neoplasia in cats poses challenges for management. Prognosis is affected by tumour size and, therefore, early recognition and treatment of mammary tumours is paramount. Although the primary tumour can be excised surgically, no studies have shown that chemotherapy significantly extends survival time; hence, metastatic spread remains an important clinical problem.

PATIENT GROUP

Mammary tumours usually affect older female cats, mainly entire females. Siamese and Oriental breeds may be predisposed. Male cats can develop mammary neoplasia, but this is rare.

EVIDENCE BASE

This review summarises the current literature relating to aetiology, pathology, presentation, diagnosis, staging, treatment and prognosis of feline mammary tumours.

摘要

实际意义

乳腺肿瘤是猫和狗中最常见的肿瘤之一,但恶性组织学类型在猫中的患病率要高得多(恶性与良性的比例至少为4:1)。

临床挑战

猫乳腺肿瘤更具侵袭性的性质给治疗带来了挑战。预后受肿瘤大小影响,因此,早期识别和治疗乳腺肿瘤至关重要。虽然原发性肿瘤可以通过手术切除,但尚无研究表明化疗能显著延长生存时间;因此,转移扩散仍然是一个重要的临床问题。

患者群体

乳腺肿瘤通常影响老年雌性猫,主要是未绝育的雌性。暹罗猫和东方品种可能易患。雄性猫也可发生乳腺肿瘤,但这种情况很少见。

证据基础

本综述总结了目前有关猫乳腺肿瘤的病因、病理、表现、诊断、分期、治疗和预后的文献。

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