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青年缺血性脑梗死

Ischaemic cerebral infarction in young adults.

作者信息

Federico F, Calvario T, Di Turi N, Paradiso F

机构信息

Università Degli Studi di Bari i Clinica Neurologica.

出版信息

Acta Neurol (Napoli). 1990 Apr;12(2):101-8.

PMID:2360474
Abstract

Fifty six patients aged 17 to 45 years who had Ischemic Cerebral Infarction (I.C.I.) were studied. The following etiologies were established: 1. Juvenile atherosclerosis (21 patients); 2. Cerebral embolism either from cardiac (10 patients) and from unknown source (3 patients); 3. Secondary coagulopathies (4 patients); 4. Non atherosclerotic vasculopathies (6 patients); 5. Traumas of skull and neck (3 patients); 6. Migraine (2 patients); 7. Oral contraceptives use (1 patient). In 6 cases the etiology remained unknown. Young subjects with I.C.I. are a heterogeneous group: however in most of them a reasonable cause can be found. The occurrence of acute death (14%) was high, while recurrent stroke (5%) and non acute death (3%) were rare when compared to older patients. At the follow-up 80% had a very little residual motor deficit but only 43% were able to return to previous work.

摘要

对56名年龄在17至45岁之间的缺血性脑梗死(I.C.I.)患者进行了研究。确定了以下病因:1. 青少年动脉粥样硬化(21例患者);2. 心脏源性脑栓塞(10例患者)和不明来源脑栓塞(3例患者);3. 继发性凝血障碍(4例患者);4. 非动脉粥样硬化性血管病变(6例患者);5. 颅脑和颈部外伤(3例患者);6. 偏头痛(2例患者);7. 使用口服避孕药(1例患者)。6例患者病因不明。患有缺血性脑梗死的年轻患者是一个异质性群体:然而,大多数患者都能找到合理的病因。与老年患者相比,急性死亡发生率(14%)较高,而复发性中风(5%)和非急性死亡(3%)较少见。随访时,80%的患者残留运动功能障碍非常轻微,但只有43%的患者能够重返工作岗位。

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