Paolino E, Granieri E, Matarese V, Poluzzi A, Casetta I
Neurological Clinic, University of Ferrara, Italy.
Acta Neurol (Napoli). 1990 Apr;12(2):122-31.
A case is reported of a primary central nervous system lymphoma in a heterosexual patient affected by acquired immunodeficiency syndrome. Because of the rarity and the aggressive diagnostic procedures, pre-mortem diagnosis is seldom established. This radiosensitive tumor, however, often contains monoclonal immunoglobulin productive cells and shows, at CT-scan, a multicentric arrangement. On this basis, a careful analysis of the cerebrospinal fluid and CT-scan may offer a possible mean of earlier diagnosis and improve the survival of these patients.
报告了一例患有获得性免疫缺陷综合征的异性恋患者发生原发性中枢神经系统淋巴瘤的病例。由于该病罕见且诊断程序具有侵袭性,生前诊断很少得以确立。然而,这种对放疗敏感的肿瘤通常含有产生单克隆免疫球蛋白的细胞,并且在CT扫描中显示为多中心分布。基于此,对脑脊液和CT扫描进行仔细分析可能为早期诊断提供一种可能的方法,并提高这些患者的生存率。