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交配型基因座在镰刀菌中的结构与功能。

Mating type loci inFusarium: structure and function.

机构信息

Biointeractions and Plant Health, Plant Research International, Droevendaalsesteeg 1, Wageningen, The Netherlands, cees.waalwljk@wurni.

出版信息

Mycotoxin Res. 2006 Mar;22(1):54-60. doi: 10.1007/BF02954558.

DOI:10.1007/BF02954558
PMID:23605502
Abstract

Sex in fungi is regulated by highly dissimilar mating type loci named idiomorphs. The genus Fusarium harbours both sexual as well as esexual species and each appears to contain one or the other idiomorph. The structure of these loci is highly conserved, suggesting a cryptic sexual cycle in these socalled asexual species. Alternatively, idiomorphs could regulate additional hitherto unrecognized biological processes. Such processes could be elucidated by expression profiling using mutants disrupted in their mating type loci.

摘要

真菌中的性别由高度不同的交配型基因座(称为异型等位基因)调控。镰刀菌属同时具有有性和无性物种,每种似乎都包含一种异型等位基因。这些基因座的结构高度保守,表明这些所谓的无性物种中存在隐性的有性周期。或者,异型等位基因可能调控其他尚未被识别的生物学过程。可以通过在交配型基因座发生突变的突变体中进行表达谱分析来阐明这些过程。

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本文引用的文献

1
Comparative analysis of 87,000 expressed sequence tags from the fumonisin-producing fungus Fusarium verticillioides.来自产伏马毒素真菌串珠镰刀菌的87000个表达序列标签的比较分析。
Fungal Genet Biol. 2005 Oct;42(10):848-61. doi: 10.1016/j.fgb.2005.06.001.
2
Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus.机会性真菌病原体烟曲霉存在性行为的证据。
Curr Biol. 2005 Jul 12;15(13):1242-8. doi: 10.1016/j.cub.2005.05.045.
3
Genetic diversity of human pathogenic members of the Fusarium oxysporum complex inferred from multilocus DNA sequence data and amplified fragment length polymorphism analyses: evidence for the recent dispersion of a geographically widespread clonal lineage and nosocomial origin.
基于多位点DNA序列数据和扩增片段长度多态性分析推断尖孢镰刀菌复合体人类致病成员的遗传多样性:一个地理分布广泛的克隆谱系近期传播及医院感染源的证据
J Clin Microbiol. 2004 Nov;42(11):5109-20. doi: 10.1128/JCM.42.11.5109-5120.2004.
4
Mating type sequences in asexually reproducing Fusarium species.无性繁殖的镰刀菌属物种中的交配型序列。
Appl Environ Microbiol. 2004 Aug;70(8):4419-23. doi: 10.1128/AEM.70.8.4419-4423.2004.
5
Genomics reveals sexual secrets of Aspergillus.基因组学揭示了曲霉菌的性别秘密。
Microbiology (Reading). 2003 Sep;149(Pt 9):2301-2303. doi: 10.1099/mic.0.C0119-0.
6
Shared ITS DNA substitutions in isolates of opposite mating type reveal a recombining history for three presumed asexual species in the filamentous ascomycete genus Alternaria.相反交配型分离株中共享的ITS DNA替换揭示了丝状子囊菌链格孢属中三个假定的无性物种的重组历史。
Mycol Res. 2003 Feb;107(Pt 2):169-82. doi: 10.1017/s0953756203007263.
7
Cloning and analysis of the mating-type idiomorphs from the barley pathogen Septoria passerinii.来自大麦病原菌雀麦壳针孢(Septoria passerinii)交配型特异序列的克隆与分析。
Mol Genet Genomics. 2003 Apr;269(1):1-12. doi: 10.1007/s00438-002-0795-x. Epub 2003 Mar 11.
8
The Neurospora crassa pheromone precursor genes are regulated by the mating type locus and the circadian clock.粗糙脉孢菌信息素前体基因受交配型位点和生物钟调控。
Mol Microbiol. 2002 Aug;45(3):795-804. doi: 10.1046/j.1365-2958.2002.03052.x.
9
Isolation and characterization of the mating-type idiomorphs from the wheat septoria leaf blotch fungus Mycosphaerella graminicola.小麦壳针孢叶斑病菌小麦壳针孢交配型特异序列的分离与鉴定
Fungal Genet Biol. 2002 Apr;35(3):277-86. doi: 10.1006/fgbi.2001.1322.
10
Molecular organization of mating type loci in heterothallic, homothallic, and asexual Gibberella/Fusarium species.异宗配合、同宗配合及无性赤霉菌/镰刀菌属物种中交配型基因座的分子组织
Fungal Genet Biol. 2000 Oct;31(1):7-20. doi: 10.1006/fgbi.2000.1226.